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Cosmetic applications of selected traditional Chinese herbal medicines.
Among active anti-tyrosinase extracts, Sophora japonica and Spatholobus suberectus were especially potent in HEMn cells in terms of free radical scavenging effects and high phenolic contents, making them the strongest candidates for cosmetic application found in the current study. Expand
Monoamine oxidase B (MAO-B) inhibition by active principles from Uncaria rhynchophylla.
The isolated two known compounds, (+)-catechin and (-)-epicatechin, isolated here for the first time from Uncaria rhynchophylla, might be able to protect against neurodegeneration in vitro, and the molecular mechanism deserves further study. Expand
The phenolic constituents and free radical scavenging activities of Gynura formosana Kiamnra
Gynura formosana Kiamnra (Compositae) is a herbal folk medicine that is a popular vegetable in Taiwan. The free-radical scavenging activities of a 70% aqueous acetone extract from the herb GExpand
Neurocytoprotective Effects of Aliphatic Hydroxamates from Lovastatin, a Secondary Metabolite from Monascus-Fermented Red Mold Rice, in 6-Hydroxydopamine (6-OHDA)-Treated Nerve Growth Factor
Compound 3f may be used as a neurocytoprotective agent against 6-hydroxydopamine (6-OHDA)-induced toxicity in human neuroblastoma PC12 cells and JC-1 staining indicated that compound 3f also stabilized mitochondrial membrane potential. Expand
The mucilage of yam (Dioscorea batatas Decne) tuber exhibited angiotensin converting enzyme inhibitory activities
The tuber mucilage of yam was extracted and purified to homogeneity and shown by spectrophotometric method to inhibit angiotensin converting enzyme (ACE) in a dose-dependent manner and mixed type inhibition against ACE was shown. Expand
Bioactive constituents of Spatholobus suberectus in regulating tyrosinase-related proteins and mRNA in HEMn cells.
It is concluded that butin is the most active of the components of S. suberectus in inhibiting pigmentation and that this inhibition is exerted through inhibition of transcription of the genes encoding tyrosinase, TRP1 and TRP2. Expand
Constituents from the Formosan apple reduce tyrosinase activity in human epidermal melanocytes.
3-hydroxyphloretin (7) and catechol (9) were the most active constituents from the Formosan apple; they exhibited anti-oxidant and tyrosinase reducing activities, suggesting their possible use as cosmetic agents. Expand
Patatin, the tuber storage protein of potato (Solanum tuberosum L.), exhibits antioxidant activity in vitro.
It was suggested that cysteine and tryptophan residues in patatin might contribute to its antioxidant activities against radicals. Expand
Neurocytoprotective effects of the bioactive constituents of Pueraria thomsonii in 6-hydroxydopamine (6-OHDA)-treated nerve growth factor (NGF)-differentiated PC12 cells.
Daidzein and genistein may be useful in the development of future strategies for the treatment of PD and exhibited neurocytoprotective effects against 6-hydroxydopamine (6-OHDA)-induced cytotoxicity in nerve growth factor (NGF)-differentiated PC12 cells. Expand
New constituent from Podocarpus macrophyllus var. macrophyllus shows anti-tyrosinase effect and regulates tyrosinase-related proteins and mRNA in human epidermal melanocytes.
Findings suggest that the new compound, 2,3-dihydro-4',4'''-di-O-methylamentoflavone (5), is the most active component of P. macrophyllus in inhibiting pigmentation and that this inhibition is exerted through inhibition of transcription of the genes encoding TRP2. Expand