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OBJECTIVE To determine oxidative stress by the level of protein carbonyls and total antioxidant status (TAOS), and whether oxidative stress is associated with increased risk of cardiovascular disease in women with polycystic ovary syndrome (PCOS). DESIGN Controlled clinical study. SETTING University hospital. PATIENT(S) Thirty women with PCOS and 31(More)
OBJECTIVE To simultaneously investigate the polysomnography (PSG) and nonstress test (NST) records of pregnant women with obstructive sleep apnea (OSA) to observe NST changes during maternal desaturation and determine maternal and fetal outcomes. METHODS A prospective observational study of pregnant women assessed by questionnaire for symptoms of OSA.(More)
AIM To investigate the relationship between Helicobacter pylori infection and severe hyperemesis gravidarum (H. Gravidarum) by using Helicobacter pylori Stool Antigen (HpSA) and other serologic test results. METHODS Twenty-seven pregnant women with H. Gravidarum and 97 asymptomatic pregnant women of matching gestational age without gastric problems were(More)
OBJECTIVE To compare the efficacy of cabergoline (Cb2) and meloxicam in curbing vascular endothelial growth factor (VEGF) expression and preventing ovarian hyperstimulation syndrome (OHSS). DESIGN Randomized controlled, animal study. SETTING Academic facility. SAMPLE We used a total of 50 immature Wistar female rats randomly to create an experimental(More)
OBJECTIVE To investigate the association between either depression or anxiety early in pregnancy, and nausea and vomiting, in a clinical sample. METHODS Anxiety and depression scores of 230 women were investigated by using the Hospital Anxiety and Depression Scale. Nausea and vomiting of pregnancy (NVP) were scored by using the Rhode's system. These(More)
BACKGROUND The study was carried out to evaluate the effects of short-term transdermal hormone replacement therapy (HRT) on glycaemic control, lipid metabolism, C-reactive protein (CRP) and proteinuria in high-risk postmenopausal women. METHODS A total of 20 well-controlled type 2 diabetic, hypertensive and 21 well-controlled glucose-tolerant,(More)
BACKGROUND Pneumoperitoneum (Pp) induces ischaemia in intra-abdominal tissues. We investigated the effects of ischaemic preconditioning (IP) and low-pressure Pp methods used to reduce ischaemic injury during Pp on oxidative stress and inflammatory cytokine response. METHODS Thirty-two rats were divided into four groups. Rats in the control group were(More)
OBJECTIVE To investigate short-term and long-term effects of combined hormone replacement therapy (HRT) on C-reactive protein (CRP) and fibrinogen plasma concentrations in healthy postmenopausal women. METHODS In this cross-sectional study 241 healthy postmenopausal women were enrolled. A total of 81 women were receiving the following treatments for 3(More)
BACKGROUND To determine the levels of oxidative stress markers in pregnant women who snore and compare with non-snoring pregnant women. Fetal outcome of these 2 groups was also evaluated. MATERIALS AND METHODS Prospective, case control study. Some 40 pregnant women who snored and 43 non-snoring pregnant women were evaluated. The glutathione peroxidase(More)
BACKGROUND PTEN seems to play an important role in cell cycle, growth, migration, and death. Integrins are cell surface receptors that play a role in the regulation of cell proliferation, differentiation, implantation, and embryogenesis. PTEN inhibits beta1 integrin signaling. The objective of this study is to investigate the expression of PTEN and beta1(More)