Mehmet Ali Darendeliler

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The aim of this study was to assess the effect of bite opening induced by a mandibular advancement splint (MAS) on efficacy and side effects in the treatment of obstructive sleep apnea. In a randomized crossover fashion, 23 adult patients received either MAS-1 (4 mm of interincisal opening) or MAS-2 (14 mm of interincisal opening) for 2 weeks, followed by(More)
INTRODUCTION Orthodontic treatment with clear sequential removable thermoplastic appliances (TAs) is gaining popularity as an alternative to treatment with fixed appliances. The amount of orthodontically induced inflammatory root resorption generated by such appliances has not been investigated. In this prospective randomized clinical trial, we used x-ray(More)
Intra-arch distal molar movement techniques have recently assumed an important role in clinical orthodontics. In this study, the dental and skeletal effects of the pendulum appliance, applying 200 to 250 g of force to the molars in 13 patients (age range 8 years to 13 years 5 months) were evaluated by means of cephalometric radiographs. The results showed(More)
RATIONALE Continuous positive airway pressure (CPAP) and mandibular advancement device (MAD) therapy are commonly used to treat obstructive sleep apnea (OSA). Differences in efficacy and compliance of these treatments are likely to influence improvements in health outcomes. OBJECTIVES To compare health effects after 1 month of optimal CPAP and MAD therapy(More)
BACKGROUND The mechanisms by which mandibular advancement splints (MAS) improve obstructive sleep apnoea (OSA) are not well understood. This study aimed to evaluate the mechanism of action of MAS by assessing their effect on upper airway structure in patients with OSA. METHODS Patients were recruited from a sleep disorders clinic for treatment with a(More)
STUDY OBJECTIVES To compare the efficacy of a mandibular advancement splint (MAS) and a novel tongue stabilizing device (TSD) in the treatment of obstructive sleep apnea (OSA). DESIGN A randomized crossover design was used. PATIENTS Twenty-seven patients (20 male, 7 female), recruited from a tertiary hospital sleep clinic. MEASUREMENTS AND RESULTS The(More)
OBJECTIVE To test the hypothesis that the administration of aspirin, acetaminophen, meloxicam, celecoxib, and prednisolone have no effect on root resorption and tooth movement. MATERIALS AND METHODS A mesial force of 50 g was applied to the left maxillary first molars of sixty 10-week-old male Wistar rats using nickel titanium closed coil springs attached(More)
A clinical study was recently undertaken to evaluate the dental and skeletal effects of the pendulum appliance (PA). In the present study, the appliance was modified by incorporating an uprighting bend into the distalizing spring during the second phase of treatment to avoid excessive distal tipping of the maxillary molars. The sample consisted of 20(More)
STUDY OBJECTIVES Mandibular advancement splints (MAS) are often preferred to CPAP treatment for OSA but are not always equally efficacious. High therapeutic CPAP pressure has been associated with MAS treatment failure in a Japanese population. We sought to assess the relationship between CPAP pressure and MAS treatment response in an Australian population.(More)
INTRODUCTION The effect of zoledronic acid, a potent and novel bisphosphonate, on tooth movement and orthodontically induced root resorption in osteoporotic animals systemically treated with zoledronic acid as similarly used in postmenopausal patients has not been elucidated. Therefore, this study was undertaken. METHODS Fifteen 10-week-old female Wistar(More)