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BACKGROUND Trastuzumab is humanized monoclonal antibody targeting her 2 neu receptor, overexpressed in 20% of breast cancers and part of the complex of Epidermal Growth Factor Receptor. AIM To review new advances in the knowledge of the practical use of "trastuzumab (Herceptin ®)" in breast cancer. METHODS Review of literature using medical data bases(More)
In a recent article Gorín and Schröder[3] study λ−simulations of coalgebras and relate them to preservation of positive formulae. Their main results assume that λ is a set of monotonic predicate liftings and their proofs are set-theoretical. We give a different definition of simulation , called strong simulation, which has several advantages: Our notion(More)
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