Meghan E Quirk

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The impact of tetrahydrobiopterin (BH4) treatment on phenylalanine tolerance, medical-food consumption, and nutrition status in patients with phenylketonuria (PKU) was investigated. Six children (5–12 years) with well-controlled PKU, responding to a BH4 dose of 20 mg/kg per day, were assessed for 24 months. Mean dietary phenylalanine tolerance increased(More)
BACKGROUND A need exists to expand the characterization of tetrahydrobiopterin (BH(4)) responsiveness in patients with phenylketonuria (PKU), beyond simply evaluating change in blood phenylalanine concentrations. The clinical interpretation of BH(4) responsiveness should be evaluated within the context of phenylalanine hydroxylase (PAH) genotype. AIM This(More)
BACKGROUND The reliability of studies investigating biological and therapeutic factors that influence body composition in PKU patients depends on accurate anthropometric measurements. OBJECTIVE To determine the precision of six anthropometric skinfold equations versus air displacement plethysmography (ADP) for predicting body fat (BF) percentage in female(More)
Tetrahydrobiopterin (BH(4)) responsiveness is currently defined as a decrease in plasma phenylalanine concentrations in patients with phenylketonuria (PKU). This definition does not offer insight beyond the initial assessment of patients, which may lead to treatment ambiguity in patients who only experience an initial decrease in plasma phenylalanine(More)
Resting energy expenditure (REE) is often used to estimate total energy needs. The Schofield equation based on weight and height has been reported to underestimate REE in female children with phenylketonuria (PKU). The objective of this observational, cross-sectional study was to evaluate the agreement of measured REE with predicted REE for female(More)
This paper describes a feasibility study for a selfcontained, wearable full-body motion capture system based on time-of-flight measurements that provide absolute distances between points on the body. Our motivation for the system is to allow an e-textile garment to sense its own shape using only body-worn sensors, thereby enabling it to dynamically adapt(More)
Electronic textile research often centers on the concept of introducing electronics to apparel such as shirts jackets, gloves, and health vests. Another less researched concept incorporates electronics into large textile surfaces such as carpets and upholstery. In this paper we explore methods and challenges of building a large surface area electronic(More)
This paper considers the impact of fabric properties on the e-textile design process. Specifically, properties such as weave pattern, drape, and weight are evaluated as physical aspects of an e-textile system within an expanded design flow. Results from woven e-textile samples are reported and analyzed, with a more detailed analysis on sensors as fibers in(More)
This paper describes an Android mobile app we developed to simplify the shopping experience of participants in the Special Supplemental Nutrition Program for Women, Infants, and Children (WIC), which provides low-income families vouchers to purchase life-stage appropriate, nutritious foods. Our app helps alleviate the tedious and error-prone use of paper(More)