Meghan E Flanigan

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J. C. Venter, M. D. Adams, +271 authors Xiaojun Zhu
Science
2001

A 2.91-billion base pair (bp) consensus sequence of the euchromatic portion of the human genome was generated by the whole-genome shotgun sequencing method. The 14.8-billion bp DNA sequence was… (More)

microRNA-206 in rat medial prefrontal cortex regulates BDNF expression and alcohol drinking.

Jenica D. Tapocik, Estelle Barbier, +7 authors Markus Heilig
The Journal of neuroscience : the official…
2014

Escalation of voluntary alcohol consumption is a hallmark of alcoholism, but its neural substrates remain unknown. In rats, escalation occurs following prolonged exposure to cycles of alcohol… (More)

Coordinated dysregulation of mRNAs and microRNAs in the rat medial prefrontal cortex following a history of alcohol dependence

J. D. Tapocik, Matthew Solomon, +6 authors Michael Heilig
The Pharmacogenomics Journal
2013

Long-term changes in brain gene expression have been identified in alcohol dependence, but underlying mechanisms remain unknown. Here, we examined the potential role of microRNAs (miRNAs) for… (More)

Loss of metabotropic glutamate receptor 2 escalates alcohol consumption.

Zhifeng Zhou, Camilla Thellenberg Karlsson, +15 authors David Goldman
Proceedings of the National Academy of Sciences…
2013

Identification of genes influencing complex traits is hampered by genetic heterogeneity, the modest effect size of many alleles, and the likely involvement of rare and uncommon alleles. Etiologic… (More)

Directional limits on persistent gravitational waves using LIGO S5 science data.

Jérôme Abadie, B. P. Abbott, +497 authors L. Pinard
Physical review letters
2011

The gravitational-wave (GW) sky may include nearby pointlike sources as well as stochastic backgrounds. We perform two directional searches for persistent GWs using data from the LIGO S5 science run:… (More)

Wistar rats acquire and maintain self-administration of 20 % ethanol without water deprivation, saccharin/sucrose fading, or extended access training

Elie Augier, Meghan E Flanigan, +6 authors J. D. Tapocik
Psychopharmacology
2014

Operant self-administration (SA) is an important model of motivation to consume ethanol (EtOH), but low rates of voluntary consumption in rats are thought to necessitate water deprivation and… (More)

Gender-dependent racial difference in disposition of cyclosporine among healthy African American and white volunteers.

David I. Min, M. Lee, Yixuan Ku, Meghan E Flanigan
Clinical pharmacology and therapeutics
2000

Pharmacokinetic studies of intravenous and oral cyclosporine (cyclosporin) were performed in 22 healthy African American (n = 11) and white (n = 11) volunteers. Blood cyclosporine concentrations were… (More)

Basal forebrain projections to the lateral habenula modulate aggression reward

Sam A Golden, Mitra Heshmati, +17 authors Scott J Russo
Nature
2016

Maladaptive aggressive behaviour is associated with a number of neuropsychiatric disorders and is thought to result partly from the inappropriate activation of brain reward systems in response to… (More)

Implementation and testing of the first prompt search for gravitational wave transients with electromagnetic counterparts

Jérôme Abadie, B. P. Abbott, +497 authors H. Ebhardt
2012

Aims. A transient astrophysical event observed in both gravitational wave (GW) and electromagnetic (EM) channels would yield rich scientific rewards. A first program initiating EM follow-ups to… (More)

Implications for the Origin of Grb 051103 from Ligo Observations

Jérôme Abadie, B. P. Abbott, +205 authors G M Harry
2012

We present the results of a LIGO search for gravitational waves (GWs) associated with GRB 051103, a short-duration hard-spectrum gamma-ray burst whose electromagnetically determined sky position is… (More)

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