Learn More
The nuclear factor kappa B (NF-κB) regulates genes that function in diverse cellular processes like inflammation, immunity and cell survival. The activation of NF-κB is tightly controlled and the deubiquitinase CYLD has emerged as a key negative regulator of NF-κB signalling. Optineurin, mutated in certain glaucomas and amyotrophic lateral sclerosis, is(More)
Large B-cell non-Hodgkin lymphoma involving the prostate accounts for 0.09% and 0.1% of non-Hodgkin lymphoma. We report a case of prostatic large B-cell non-Hodgkin lymphoma in a 77-year-old male with symptoms of urinary retention most probably due to benign prostate hyperplasia. He underwent multiple needle core biopsies through transrectal ultrasound of(More)
for his work that helped in understanding the molecular mechanisms of autophagy, a process used by most eukaryotic cells to degrade a portion of cytoplasm including damaged organelles, large protein complexes and aggregated proteins in lysosomes. This process of autophagy (self-eating) maintains cellular homeostasis and helps the cell and the organism to(More)
  • 1