Megan E. Rokop

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Although it is widely regarded that the targeting of RNA molecules to subcellular destinations depends upon the recognition of cis-elements found within their 3' untranslated regions (UTR), relatively little is known about the specific features of these cis-sequences that underlie their function. Interaction between specific repeated motifs within the 3'(More)
BACKGROUND The Bacillus subtilis genes dnaD and dnaB are essential for the initiation of DNA replication and are required for loading of the replicative helicase at the chromosomal origin of replication oriC. Wild type DnaD and DnaB interact weakly in vitro and this interaction has not been detected in vivo or in yeast two-hybrid assays. (More)
Teaching about proteins, how their structure is specified, and how in turn this influences their function has become an integral curriculum component for both introductory biology and biochemistry undergraduate courses. To understand how proteins work, students first learn about protein structure and its relationship to protein function. StarBiochem is a(More)
Origin of exocrine pancreatic cells from nestin-positive precursors in developing mouse pancreas 15 Ce-Y14 and MAG-1, components of the exon–exon junction complex, are required for embryogenesis and germline sexual switching in Caenorhabditis elegans 27 The grainy head transcription factor is essential for the function of the frizzled pathway in the(More)
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