Megan Bale Nelson

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A developmental progression of histochemical fiber typing is demonstrated in normal rat soleus muscle. By utilizing the acid lability of ATPase, the type II fibres are subdivided into type IIA, IIB and IIC. No IIB fibers are present in the newborn or adult rat soleus. In the 1-day-old animal 90% of the fibers can be differentiated into type I and II with(More)
The histology of muscle obtained from 23 hypotonic infants without neuromuscular disease is presented. Long-term follow-up neurological examinations were carried out to determine the site of the lesion. 18 cases have strong evidence of cerebral dysfunction, 12 of whom have histologial abnormalities of fiber-type distribution and diameter. Of the remaining(More)
OBJECTIVE Demonstrate the inpatient rehabilitation potential of cerebellopontine angle epidermoid cyst patients. Due to their location, symptoms may present with a complex combination of headache, cerebellar dysfunction, and cranial nerve deficits affecting functional status. METHODS This report describes the cases of 3 patients with cerebellopontine(More)
The results of needle biopsies of muscle in 14 infants (age-range four months to 3 years 3 months) with marked hypotonia are presented. In adults, needle biopsies of muscle have been used to aid in the diagnosis of neuromuscular disorders, with considerable success. The simplicity of the method and the high quality of the samples obtained in the present(More)
During my cancer rehabilitation fellowship training, cancer patients graciously provide me with mental, emotional, and educational snapshots of their lives. I learn from them daily as they immerse themselves in a unique setting surrounded by dedicated inpatient cancer rehabilitation team members. Our cancer patients have various diagnoses: some are(More)
Eighteen-month-old identical twins with the muscle histological characteristics of congenital fiber type disproportion are reported. The fiber typing system of pH-dependent adenosine triphosphatase was used to analyze the size and percentage of type 1, 2A, and 2B fibers in muscle tissue obtained by needle biopsy. Both twins had significantly larger type 2(More)
Previous studies involving the induction of central nervous system lesions in animals have required complex, expensive equipment including sterotaxis and an operating microscope. This study describes a technique for producing telencephalic (forebrain) lesions in the developing rat by the use of copper wire. In addition, a nonvisual method of producing(More)
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