Meenal Soni

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The conversion of the genomic information produced by the recent sequencing projects into a comprehensive understanding of the human proteome has yet to occur. A new technology that represents a potential bridge between genomics and proteomics is reverse transfection. Reverse transfection cell microarrays are produced by overlaying cDNA arrays with(More)
Analysis of the human genome sequence has identified thousands of putative genes with unknown function; therefore, a new tool allowing for rapid identification of gene functions is needed. Reverse transfection microarray technology, which turns a DNA microarray into a cell-based microarray, has emerged for simultaneously studying the function of many genes.(More)
This article presents a brief overview of label-free optical biosensor-based cell assay technologies. Theoretical analysis suggests that a resonant waveguide grating (RWG) biosensor detects ligand-induced dynamic mass redistribution (DMR) within the bottom portion of an adherent cell layer. Pharmacological studies suggest that the DMR signal can serve as a(More)
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