Meenakshi Jayaraman

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With the etiology being unclear till date, a combination of age, genetic and environmental factors are known to play a significant role in the pathogenesis of Parkinson's disease. Mutations in PARK2 gene have been implicated to cause autosomal recessive early onset PD. We analyzed the 12 coding exons of PARK2 gene in 16 early onset PD patients of South(More)
Keloids are manifestations of abnormal wound repair with unresolved clinical complications. An effective therapeutic regimen has not been established for keloids, and current strategies are plagued by problems such as recurrence and side effects. Keloids, being a human-specific dermal fibroproliferative disorder are characterized by an excessive(More)
Parkinson’s disease (PD) is the second most common neurodegenerative disorder characterized by the loss of dopaminergic neurons. Mutations in genes a-Synuclein (SNCA), Parkin (PARK2), Leucinerich repeat kinase 2 (LRRK2), PTENinduced putative kinase 1 (PINK1) and PARK 7 (DJ-1) have been firmly established to cause mendelian forms of PD. SNCA, the first known(More)
Efficient DC to DC and DC to AC converters play a vital role in the reliable performance of standalone and grid connected photovoltaic systems. This paper deals with DC to AC conversion by a seven level cascaded H-bridge multilevel inverter for a standalone photovoltaic system. The PV fed seven level cascaded H-bridge multilevel inverter is analyzed in two(More)
Multilevel inverters are popular for renewable energy applications. This paper presents a technique for harmonic elimination in a five level cascaded H-Bridge multilevel inverter. The technique is based on computation of switching angles using Chebyshev polynomials. The method involves simple mathematical calculations to arrive at the desired switching(More)
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