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OBJECTIVES The longevity of homografts is determined by the activation of the recipients' immune system resulting from allogenic antigen exposition. Fresh decellularized pulmonary homografts (DPH) have shown promising early results in pulmonary valve replacement in children and young adults and could potentially avoid significant activation of the immune(More)
OBJECTIVE The Fontan operation has been proposed as definitive palliation for an increasing variety of hearts with complex univentricular anatomy, but late morbidity after Fontan operation is still a matter of concern. This retrospective study evaluates the late outcome in patients with Fontan circulation. METHODS We included 121 consecutive patients that(More)
Since a growing number of patients after surgical repair of transposition of the great arteries (TGA) survive until adulthood the focus of attention has shifted to the management of associated long-term morbidity and quality of life (QoL). Therefore, we reviewed all patients that underwent surgical repair of TGA at our institution and compared long-term(More)
In women with Marfan syndrome pregnancy increases the risk of aortic dissection. There are a number of articles reporting the outcome of acute aortic dissection during pregnancy in this patient group. In contrast, only scarce information is available concerning pregnancy in patients with pre-existing chronic aortic dissection. We report the case of a(More)
Conventional two-dimensional (2-D) texture parameters serve as the "gold standard" of texture analysis. The authors compared a new stochastic model, based on autoregressive periodic random field models (APRFM) with conventional texture analysts (CTA) parameter, which were defined as measures of the co-occurrence matrix, i.e., entropy, contrast, correlation,(More)
OBJECTIVES This study evaluated the application of ultrasound (US) guidance in the percutaneous placement of gastric feeding tubes in patients in whom endoscopic placement of a nutrition tube is not possible. METHODS Thirty-eight patients with upper gastrointestinal obstruction were entered in a prospective study with US-guided nutrition tube application.(More)
OBJECTIVE As mortality and morbidity after the Fontan operation has improved, long-term outcome, including developmental aspects, have become more important. To understand the long-term effects of this operation, we followed somatic development for up to 15 years. METHODS We evaluated 90 patients who underwent the Fontan operation between 1984 and 2004(More)
BACKGROUND Chronic severe pulmonary regurgitation (PR) causes progressive right ventricular (RV) dysfunction and heart failure. Parameters defining the optimal time point for surgery of chronic PR are lacking. The present study prospectively evaluated the impact of preoperative clinical parameters, cardiorespiratory function, QRS duration and NT-proBNP(More)
OBJECTIVE Homografts are considered the gold standard for right ventricular outflow tract reconstruction. Their long-term durability is limited, and alternatives became available. We evaluate their long-term hemodynamic performance to permit comparisons with alternative devices. METHODS Between 1985 and 2004, 188 homografts were implanted in pulmonary(More)