The effect of acute and chronic administration of the 5-HT1A agonist buspirone on successive negative contrast was investigated in Experiments 1-6. Contrast in consummatory behavior was induced by shifting rats from a 32% to a 4% sucrose solution. Experiments 1-5 showed that buspirone (0.125, 0.25, 0.5, 1.0, 2.0, 15.0 mg/kg) was ineffective in alleviating… (More)
Medical providers are trained to investigate, diagnose, and treat cancer. Their primary goal is to maximize the chances of curing the patient, with less training provided on palliative care concepts and the unique developmental needs inherent in this population. Early, systematic integration of palliative care into standard oncology practice represents a… (More)
BACKGROUND Given the burden of childhood cancer and palliative care need in Africa, this paper investigated the paediatric and palliative care elements in cancer control plans. METHODS We conducted a comparative content analysis of accessible national cancer control plans in Africa, using a health systems perspective attentive to context, development,… (More)
BACKGROUND Retinoblastoma, the most common intraocular tumor globally, represents a curable cancer when diagnosed early and treated promptly. Delay to diagnosis, lag time prior to treatment initiation, and abandonment of treatment including upfront treatment refusal, represent stark causes of high retinoblastoma mortality rates in low- and middle- income… (More)
An experiment manipulating both reward-magnitude contrast and delay of reinforcement is reported. The results indicated that odor cues are produced under conditions of delayed large-reward versus nonreward contrast but not under large- versus small-reward contrast. Additional magnitude and delay manipulations that resulted in the elimination of odor-based… (More)
Upon reaching maturity the offspring (N = 88) of animals exposed during pregnancy to ethanol and plain water, respectively, served as Ss in a shock-elicited aggression test. Significantly higher levels of aggression were shown by those animals that had received prenatal ethanol exposure. Several ethanol-related birth effects were also noted.
Two groups of pregnant rats (n = 10) received exposure to either 10% ethanol or water. All male offspring (n = 43) received a six-day preference test (ethanol vs water) at 90 days of age. Fluid consumption scores indicated a significant preference for water by all Ss. However, those animals receiving prenatal ethanol exposure consumed significantly more… (More)
In a test of competing hypotheses regarding the effects of alcohol on shock-elicited aggression, animals maintained on a food restricted regimen were administered either chronic or acute ethanol challenges. Chronic Ss showed a significantly higher rate of target-directed aggression and spent significantly more time in aggressive activity than did acute or… (More)