Protein tyrosine phosphatase 1B (PTP1B) is a member of the non-transmembrane phosphotyrosine phosphatase family. Recently, PTP1B has been proposed to be a novel target of anti-cancer and anti-diabetic drugs. However, the role of PTP1B in the central nervous system is not clearly understood. Therefore, in this study, we sought to define PTP1B’s role in brain… (More)
Pyruvate dehydrogenase (PDH) kinases (PDKs) 1-4, expressed in peripheral and central tissues, regulate the activity of the PDH complex (PDC). The PDC is an important mitochondrial gatekeeping enzyme that controls cellular metabolism. The role of PDKs in diverse neurological disorders, including neurometabolic aberrations and neurodegeneration, has been… (More)
Floral organ identity and specific number directly affect anthesis habits, fertilization and grain yield. Here, we identified a deformed interior floral organ 1 (difo1) mutant from selfing progenies of indica cv. Zhonghui8015 (Zh8015) after 60Co γ-ray treatment. Compared with the Zh8015 spikelet, the interior floral organs of the difo1 mutant present… (More)
Acetylcholinesterase (AChE) is demonstrated, apparently for the first time, in developing embryos of the tick Hyalomma rufipes. The enzyme was detected in the neuropile of the oesophageal ganglia and in the nerve endings of the appendages; it was absent from the neurons and neurolemma of the nerve ganglia.