Md. Ashraful Hasan

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This study was undertaken to investigate the effect of nitrogen dioxide on some neurochemical parameters. Guinea-pigs were exposed to NO2, 5 p.p.m. and 10 p.p.m. for 2 hr daily for five weeks. The results showed significant depletion of the total lipids and phospholipids content of the cerebral hemisphere, cerebellum, midbrain and spinal cord following(More)
Monoamine levels, MAO activity and neurobehavioral perturbations were studied in albino rats intoxicated with Dimecron i.e., phosphamidon (2.0 mg/kg b wt, ip x 7 days). Open field behaviour (OFB) of the rats was examined thrice a day for seven days. Significant depletion in DA, NE and 5-HT, and enhancement of MAO were found in various regions of the central(More)
DDVP is an organophosphate pesticide whose neurotoxicity, in the form of cholinesterase inhbition, is well-known. Rats, weighing 200-225 g were given intraperitoneal injections of 3 mg/kg. DDVP daily for 10 days. Following perfusion-fixation, ultrathin sections of the cerebellum and spinal cord were examined with an electron microscope. A large number of(More)
The levels of dopamine, noradrenaline and 5-hydroxytryptamine were estimated in the hypothalamus and limbic areas, corpus striatum, cerebellum and the brain-stem of rats administered thallous acetate (5 mg/kg i.p.) daily for 7 days. Significant decreases in the concentration of dopamine occurred in the hypothalamus, limbic areas and corpus striatum.(More)
The caudal part of the fourth ventricle in adult rhesus monkeys, of both sexes, revealed the area postrema (AP) to be composed of bilateral spindle-shaped elevations located ventromedial to the gracile tubercles. Supraependymal (SE) elements, comprised of SE cells and/or fibre processes could be seen near the medial margin of a narrow oligociliated strip(More)
Dichlorvos (O,O-dimethyl-2:2-dichlorovinyl phosphate) was administered IP (3 mg/kg) daily for 10 days to a group of albino rats. Open field behavior was significantly depressed below the mean of the control group. On day 7, ambulation was reduced to 24% of the mean but recovered to 60% on day 10. Similarly, rearing response was decreased on day 7 and showed(More)
Rats were given thallium acetate (5 mg elemental thallium/kg body weight) intra-peritoneally daily for 7 days. The brain was fixed by perfusion-fixation and small pieces of the cerebellum were processed for electron microscopy. Variegated mitochondrial profiles, increased incidence of electron--dense bodies and proliferation of Golgi zones were observed in(More)
N-acetyl-L-cysteine (NAC) and cysteine have been implicated in a number of human neutrophils' functional responses. However, though Ca(2+) signaling is one of the key signalings contributing to the functional responses of human neutrophils, effects of NAC and cysteine on intracellular calcium concentration ([Ca(2+)]i) in human neutrophils have not been(More)
Nucleotide (DNA) sequence analysis provides important clues regarding the characteristics and taxonomic position of an organism. With the intention that, DNA sequence analysis is very crucial to learn about hierarchical classification of that particular organism. This dataset (patent US 7547531) is chosen to simplify all the complex raw data buried in(More)
BACKGROUND Acanthopanax divaricatus var. albeofructus (ADA) extract has been reported to have anti-oxidant, immunomodulatory, and anti-mutagenic activity. MATERIALS/METHODS We investigated the effects of ADA extract on two mouse models of Alzheimer's disease (AD); intracerebroventricular injection of β-amyloid peptide (Aβ) and amyloid precursor(More)