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Snake venom proteins belong to various families which differ in their primary and secondary structures. Recently , we found a novel transcript in the venom gland of Sistrurus catenatus edwardsii which was named " Ku-wap-fusin " because it encodes Kunitz-type serine protease inhibitors (Kunitz SPIs) and whey acidic protein (WAP) domains in tandem. We have(More)
BACKGROUND Toxin profiling helps in cataloguing the toxin present in the venom as well as in searching for novel toxins. The former helps in understanding potential pharmacological profile of the venom and evolution of toxins, while the latter contributes to understanding of novel mechanisms of toxicity and provide new research tools or prototypes of(More)
The complete sequence characterization of snake venom proteins by mass spectrometry is rather challenging due to the presence of multiple isoforms from different protein families. In the present study, we investigated the tryptic digest of the venom of the viperid snake Sistrurus catenatus edwardsii by a combined approach of liquid chromatography coupled to(More)
In this study, the antioxidative fraction of white mulberry (Morus alba) was found to have an apotogenic effect on Ehrlich's ascites carcinoma cell-induced mice (EAC mice) that correlate with upregulated p53 and downregulated NFκB signaling. The antioxidant activities and polyphenolic contents of various mulberry fractions were evaluated by(More)
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