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Increased production of advanced glycosylation end products (AGEs) and augmented oxidative stress may contribute to vascular complications in diabetes. Little is known about the formation and… (More)
Advanced glycation end-products (AGEs) are formed over several weeks to months by non-enzymatic glycation and oxidation ("glycoxidation") reactions between carbohydrate-derived carbonyl groups and… (More)
Hypertension may be due to volume overload, the pressor effect of circulating agents such as renin or, theoretically, to reduced levels of circulating vasodilator agents. Certain prostaglandins, e.g.… (More)
Erythrocyte intracellular sodium concentration (IcNa, mmol/1) Na22 efflux rate constant (NaERC) and H3 ouabain binding to receptor sites on the Na-K pump (Bmax, nmol/l cells) were measured in normal… (More)
Rapid perfusion of oxygen in infants at birth may increase oxidative stress which has been incriminated in serious diseases including neonatal respiratory distress syndrome, chronic lung disease, and… (More)