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OBJECTIVE Most young women initiate sexual activity during adolescence; risk for sexually transmitted infections (STIs) accompanies this initiation. In this study we estimated the prevalence of the most common STIs among a representative sample of female adolescents in the United States. METHODS Data were analyzed from 838 females who were aged 14 to 19(More)
The results of the first Critical Assessment of Fully Automated Structure Prediction (CAFASP-1) are presented. The objective was to evaluate the success rates of fully automatic web servers for fold recognition which are available to the community. This study was based on the targets used in the third meeting on the Critical Assessment of Techniques for(More)
We evaluated the prevalence of antibodies to human papillomavirus (HPV) type 16 in a representative sample of children 6-11 years of age in the United States. Serum samples and questionnaire data were collected between 1991 and 1994, for the National Health and Nutrition Examination Survey III. HPV-16-specific immunoglobulin G antibodies were detected by an(More)
Seroprevalence of and coinfection with herpes simplex virus type 1 (HSV-1) and type 2 (HSV-2) in the United States were analyzed by use of data from a nationally representative survey (National Health and Nutrition Examination Survey III, 1988– 1994). Evidence was explored for possible protection by prior HSV-1 infection against infection and clinical(More)
BACKGROUND Nationally representative surveys of chlamydia and gonorrhea are an important measure of disease burden and progress of screening programs. OBJECTIVE To measure chlamydia and gonorrhea prevalence in the United States. DESIGN Analysis of sexual history information and urine specimens collected in the National Health and Nutrition Examination(More)
Human papillomavirus (HPV) infection is a necessary but not sufficient cause of cervical cancer. While chlamydia infection has been associated with cervical cancer, the meaning of this association remains unclear. The authors' objective was to investigate this association by evaluating whether concurrent genital tract infections are associated with HPV(More)
OBJECTIVE To evaluate the relationship between self-reported correct and consistent condom use and chlamydial and gonococcal infection. DESIGN Cross-sectional study. SETTING An urban adolescent health care clinic. Patients A total of 509 adolescent girls tested for Chlamydia trachomatis and Neisseria gonorrhoeae infection by urine nucleic acid(More)
We conducted spatial regression analysis to account for spatial clustering of sexually transmitted diseases (STDs) and to examine the state-level association between social capital (using Putnam's public use data set) and rates of gonorrhea and syphilis. We conducted the analysis for the 48 contiguous states of the United States for 1990, 1995, and 2000 and(More)
RATIONALE Chronic cocaine use results in long-lasting neurochemical changes that persist beyond the acute withdrawal period. Previous work from our group reported a profound reduction in the acoustic startle response (ASR) in chronic cocaine-dependent subjects in early abstinence compared to healthy controls that may be related to long-lasting(More)
Concern about the potentially diabetogenic effect of antipsychotics has existed since the introduction of chlorpromazine in the 1950s. However, there is controversy as to whether the newer "atypical" antipsychotics are more diabetogenic than older "typical" agents. We undertook a retrospective cohort analysis of 484 patients receiving outpatient(More)