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PURPOSE To compare directly the effect of intensity-modulated radiotherapy (IMRT) vs. conventional radiotherapy (CRT) on salivary flow and quality of life (QoL) in patients with early-stage nasopharyngeal carcinoma (NPC). METHODS AND MATERIALS Fifty-one patients with T2, N0/N1, M0 NPC took part in a randomized controlled clinical study and received IMRT(More)
BACKGROUND Removal of teeth results in both horizontal and vertical changes of hard and soft tissue dimensions. The magnitude of these changes is important for decision-making and comprehensive treatment planning, with provisions for possible solutions to expected complications during prosthetic rehabilitation. OBJECTIVES To review all English dental(More)
PURPOSE This study evaluated the mutational profile of epidermal growth factor receptor (EGFR) and KRAS in non-small cell lung cancers in Hong Kong and determined their relation with smoking history and other clinicopathologic features. EXPERIMENTAL DESIGN Mutational profile of exons 18 to 21 of EGFR and codons 12, 13, and 61 of KRAS were determined in(More)
OBJECTIVES This field demonstration trial evaluates the long-term effects of introducing daily toothbrushing with fluoride toothpaste in a Chinese kindergarten (test group) compared to caries development in children who had no organized preventive program (control group). METHODS In the test group teacher-supervised toothbrushing was initiated with 1,000(More)
The study aimed to describe and compare the psychosocial and functional impact of oral disease on the quality of life of the institutionalized and non-institutionalized elderly in Hong Kong. A total of 268 institutionalized and 318 non-institutionalized elderly aged 60-80 years took part. The 49-statement Oral Health Impact Profile (OHIP) was administered(More)
The objectives of the study were to describe the oral health status and treatment needs of the 5- to 6-year-old and 12-year-old children in Southern China; to describe the patterns of oral health behaviors, knowledge, and attitudes among the 12-year-olds; and to assess the effects of socio-behavioral factors on the 12-year-old children's dental caries(More)
Although the complications of head and neck radiotherapy in the treatment of nasopharyngeal carcinoma (NPC) have been described, there is limited information on the effect of oral complications on oral health related quality of life. The aim of this study was to describe the psychosocial and functional impact of oral conditions in southern Chinese following(More)
OBJECTIVES To translate the original English version of Oral Health Impact Profile (OHIP) into a Chinese version, to validate the translated instrument for use among the elderly in Hong Kong and to derive a Chinese short-form OHIP. METHODS The original English version of OHIP was translated into Chinese. Elderly persons aged 60-80 years were interviewed(More)
OBJECTIVE To measure the oral health status of southern Chinese nasopharyngeal carcinoma (NPC) survivors 1-4 years after radiotherapy. SUBJECTS AND METHODS A total of 109 subjects participated in this cross-sectional study. Thirty-eight subjects were NPC survivors, 40 subjects were patients newly diagnosed with NPC and 31 were healthy subjects. Verified(More)
OBJECTIVES To investigate the incidence of rehardening of caries lesions in children in Southern China taking part in a preventive programme. DESIGN Longitudinal study. SAMPLE AND METHODS A prevention programme was established for 168 3-6-year-old children in a kindergarten (KG1), which included regular oral health education sessions and a daily(More)