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Reactive case detection of Plasmodium falciparum in western Kenya highlands: effective in identifying additional cases, yet limited effect on transmission
TLDR
Screening index case households and neighbours approximately doubles the chance to detect asymptomatic infections compared to randomly selected households, which is potentially a cost-effective way towards achieving malaria elimination. Expand
Epidemiological risk factors for clinical malaria infection in the highlands of Western Kenya
TLDR
The identification of risk factors for clinical malaria infection provides information on the local malaria epidemiology and has the potential to lead to a more effective and targeted use of malaria control measures. Expand
Age-specific Plasmodium parasite profile in pre and post ITN intervention period at a highland site in western Kenya
TLDR
The study provides evidence for reduction of malaria prevalence following the introduction of LLINs and ACT in western Kenya and implies that a more comprehensive integrated malaria management may be required to sustain the current interventions and hence reduce malaria transmission. Expand
Influence of blood meal and age of mosquitoes on susceptibility to pyrethroids in Anopheles gambiae from Western Kenya
TLDR
The results showed that mosquito age and blood feeding status confers increased tolerance to insecticides as blood feeding may be playing an important role in the toxicity of deltamethrin, allowing mosquitoes to rest on insecticide-treated materials despite treatment. Expand
Resting behaviour of malaria vectors in highland and lowland sites of western Kenya: Implication on malaria vector control measures
Background Understanding the interactions between increased insecticide resistance and resting behaviour patterns of malaria mosquitoes is important for planning of adequate vector control. ThisExpand
Impact of Insecticide Resistance on P. falciparum Vectors' Biting, Feeding, and Resting Behaviour in Selected Clusters in Teso North and South Subcounties in Busia County, Western Kenya
TLDR
A shift in resistant Anopheles gambiae sl highest peak hour of aggressiveness from 2100-2200 hrs to 0300-0400‬hrs is a key change in its biting pattern. Expand
Species Composition, Phenotypic and Genotypic Resistance Levels in Major Malaria Vectors in Teso North and Teso South Subcounties in Busia County, Western Kenya
TLDR
Both phenotypic and genotypic insecticide resistance levels have been confirmed in Teso North and Teso South subcounties in Western Kenya and it is likely that resistance is likely to persist and or increase if monomolecules of permethrin and deltamethrin or both continue to be used in all net- and nonnet-based mosquito control purposes. Expand
Phenotypic, genotypic and biochemical changes during pyrethroid resistance selection in Anopheles gambiae mosquitoes
TLDR
Pre-exposure to the synergist piperonyl butoxide restored the susceptibility to insecticide among the highly resistant mosquitoes, confirming the role of monooxygenases in pyrethroid resistance. Expand
Insecticide resistance status of indoor and outdoor resting malaria vectors in a highland and lowland site in Western Kenya
TLDR
High phenotypic, metabolic and genotypic insecticide resistance in indoor resting populations of malaria vectors compared to their outdoor resting counterparts is recorded. Expand
Effects of kdr gene frequencies on major malaria vectors’ resting behaviour in Teso sub-counties, western Kenya
TLDR
Resting behaviour in Anopheles gambiae sensu lato was dependent on malaria vector resistance status and type of species, and repeated exposure of mosquitoes to insecticidal indoor environments may have led to behavioural resistance and or avoidance. Expand
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