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The lack of axonal regeneration in the injured adult mammalian spinal cord leads to permanent functional disabilities. The inability of neurons to regenerate their axon is appreciably due to an inhospitable environment made of an astrocytic scar. We generated mice knock-out for glial fibrillary acidic protein and vimentin, the major proteins of the(More)
Adult human and rodent brains contain neural stem and progenitor cells, and the presence of neural stem cells in the adult rodent spinal cord has also been described. Here, using electron microscopy, expression of neural precursor cell markers, and cell culture, we investigated whether neural precursor cells are also present in adult human spinal cord. In(More)
We have recently shown that tanycytes present in the median eminence (ME) constitute a preferential support for the regeneration of lesioned neurohypophysial oxytocinergic and vasopressinergic axons. However, although tanycytes are particularly abundant in the ME, they are also present along the third ventricle wall. This study was thus undertaken to(More)
Tanycytes present in the mediobasal hypothalamus are able to support axonal regeneration and neuron survival. Pilot experiments of transplantation of these cells into various lesioned areas of the central nervous system (CNS) were thus performed to determine whether these cells could support the regeneration of the lesioned axons. These pilot experiments,(More)
In the brain of adult rodents, young neurons arising from the subventricular zone (SVZ) of the lateral ventricle migrate tangentially along the rostral migratory stream (RMS) toward the olfactory bulb. The aim of this study was to determine whether surgical lesions placed through the RMS could affect the rostral migration of these newly formed neurons.(More)
During past years a number of therapeutic strategies have been developed in order to stimulate axonal regeneration after traumatic injuries of the spinal cord. Recently, encouraging data have been obtained by grafting specific glial cells such as Schwann cells or olfactory ensheathing glial cells, known to support the regeneration of peripheral or central(More)
Single anion selective channels have been studied in membrane patches of GBK cultured epithelial cells from bovine kidney. High conductance anion channels are exclusively observed in excised patches after holding them at membrane potentials larger than +/- 30 mV for seconds or minutes. Once activated, the channels show a steep voltage dependence, complex(More)
This paper addresses the implementation of a 2-D Discrete Wavelet Transform on general-purpose microprocessors, focusing on both memory hierarchy and SIMD parallelization issues. Both topics are somewhat related, since SIMD extensions are only useful if the memory hierarchy is efficiently exploited. In this work, locality has been significantly improved by(More)
Background The process of educating people in OT is an ongoing challenge which has many unanswered questions, and while many good pedagogical ideas are presented at conferences and published in proceedings and journals each year, very little has been done to collate the effective practices of many OT educators into one publication. Our aim is to do just(More)