Maximilian Graf

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We have developed a method to analyze in detail, translocation events providing a novel and flexible tool for data analysis of nanopore experiments. Our program, called OpenNanopore, is based on the cumulative sums algorithm (CUSUM algorithm). This algorithm is an abrupt change detection algorithm that provides fitting of current blockages, allowing the(More)
Ultrathin nanopore membranes based on 2D materials have demonstrated ultimate resolution toward DNA sequencing. Among them, molybdenum disulfide (MoS2) shows long-term stability as well as superior sensitivity enabling high throughput performance. The traditional method of fabricating nanopores with nanometer precision is based on the use of focused(More)
Today’s vehicles include up to seventy networked electronic platforms handling simultaneously infotainment and safety functions. Fully connected to the world, the car is now customizable, communicates with several external devices, online services and will be soon hosting third party applications, as our smartphones already do. Such an evolution raises(More)
Transcription is the first step in gene expression where DNA is copied into RNA. It is extensively studied at the bulk level especially the regulation mechanism, which in cancerous cells is impaired. We were interested in studying E. coli RNAP enzyme at the single-molecule level for its functional as well as molecular motor properties. With nanopore(More)
The thermally driven circulation between the European Alps and the Alpine foreland—named Alpine pumping—occurs regularly under clear and calm weather conditions. While previous studies focused on the impact of Alpine pumping on moist convection and transport of air pollutants, this study was motivated by its ventilation effect for Munich, located about 50(More)
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