Max Wunderlich

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An abdominoperineal operation is described that extends rectal resection for low tumours into the intersphincteric plane with removal of the internal sphincter. Bowel continuity is restored by coloanal anastomosis. Of 38 patients who underwent surgery since 1984, 34 had low rectal cancer and four carcinoid or large villous adenoma. There was no mortality.(More)
BACKGROUND Physical performance often declines in middle age, but it is unclear to what extent this is due to biological aging. It can be difficult to determine whether such physical changes are truly age-related, as they might alternatively be explained as the negative consequences of a sedentary lifestyle. METHODS We assessed the endurance of a(More)
The purpose of this study was to compare prospectively the diagnostic yield of anal endosonography (AES) and magnetic resonance imaging (MRI) in the assessment of perianal fistulae and abscesses. There were 39 patients (14 men, 25 women; mean age, 40 years) who underwent AES, performed with a 10-MHz rotating endoanal probe and MRI at 1.0 T (axial and(More)
A prospective study was undertaken of the incidence, symptoms, diagnostic measures and therapy of local recurrences of colorectal carcinoma following radical surgical management. Out of 715 patients, 156 (22 per cent) developed recurrence of the tumour, which was local in 90 patients. In addition, 36 patients with local recurrence from other hospitals were(More)
Unilateral pudendal neurectomy in the monkey results in histological changes consistent with partial denervation on both sides of the external anal sphincter muscle, but much more marked ipsilaterally than contralaterally. Histological features consistent with reinnervation developed during the 9-13 weeks after unilateral neurectomy in the anterior parts of(More)
OBJECTIVE Blood supply of the lungs during total cardiopulmonary bypass (CPB) is limited to flow through the bronchial arteries. This study was undertaken to assess the bronchial artery blood flow during CPB with fluorescent microspheres in a piglet model. METHODS We subjected ten piglets (mean weight 5.0+/-0.5 kg) to 120 min of normothermic, total CPB(More)
Betweeen 1965 and 1984 in 215 patients with colorectal cancer an extended resection was performed due to invasion of adjacent organs. 158 patients were operated on primary and 57 patients on recurrent tumors. Most of the tumors were localized in the sigma and the rectum and therefore about 77% of the resected organs derived from the urogenital tract. 55% of(More)
Double-contrast barium enema (DCBE) studies showed lymphoid follicular hyperplasia (LFH) in excluded colonic segments after colostomy in 12 of 40 patients. In most patients with LFH, more than 80% of the excluded colon was affected. In eight patients, regression of LFH was demonstrated with DCBE studies after reanastomosis. This work suggests that LFH is(More)
BACKGROUND Recent studies show that habits detrimental to health are becoming established ever earlier in life. Because most of these investigations focus on adolescents up to the age of 18 years, it is largely unknown whether and to what extent negative behavioral modifications are intensified in young adults. METHODS Within the cross-sectional study(More)