Learn More
BACKGROUND Walking instability and a higher risk of falls are common in patients with peripheral neuropathy. However, it remains uncertain as to whether alterations in neuropathic gait are directly related to deficient sensory locomotion control or due to a slowing of walking speed. By means of a multi-speed gait assessment we determined factors related to(More)
This review shows that persons with visual height intolerance or acrophobia exhibit typical restrictions of visual exploration and imbalance during stance and locomotion when exposed to heights. Eye and head movements are reduced, and gaze freezes to the horizon. Eye movements tend to be horizontal saccades during stance and vertical saccades during(More)
BACKGROUND Subjective postural imbalance is a key symptom in the somatoform phobic postural vertigo (PPV). It has been assumed that more attentional control of body posture and / or co-contraction of leg muscles during standing is used to minimize the physiological body sway in PPV. Here we analyze nonlinear variability of body sway in patients with PPV in(More)
OBJECTIVE This study investigated the influence of impaired cerebellar locomotion function on the magnitude and structure of stride-to-stride fluctuations in the walking pattern. On the basis of studies reporting a dependency of variability magnitude and structure on the walking speed, we hypothesized that patients with cerebellar ataxia (CA) would show(More)
Phobic postural vertigo (PPV) is characterized by a subjective dizziness and postural imbalance. Changes in postural control strategy may cause the disturbed postural performance in PPV. A better understanding of the mechanisms behind this change in strategy is required to improve the diagnostic tools and therapeutic options for this prevalent disorder.(More)
INTRODUCTION Visual height intolerance (vHI) manifests as instability at heights with apprehension of losing balance or falling. We investigated contributions of visual feedback and attention on gait performance of subjects with vHI. MATERIALS AND METHODS Sixteen subjects with vHI walked over a gait mat (GAITRite®) on a 15-m-high balcony and at(More)
The reversible potassium channel blocker 4-aminopyridine is effective in the treatment of numerous cerebellar dysfunctions, such as episodic ataxia type 2 and downbeat nystagmus syndrome. In 2011, its sustained release form, dalfampridine, was admitted in Europe for the treatment of walking difficulties in patients with multiple sclerosis (MS). Here we(More)
Falls are common in patients with cerebellar ataxia (CA). Identification of gait variables associated with a higher risk of falls allows us to detect fallers and initiate protective procedures early. Gait variability, which is increased in CA patients, is a good predictor of falls in elderly subjects and patients with neurodegenerative diseases. The(More)
OBJECTIVE Automated pattern recognition systems have been used for accurate identification of neurological conditions as well as the evaluation of the treatment outcomes. This study aims to determine the accuracy of diagnoses of (oto-)neurological gait disorders using different types of automated pattern recognition techniques. METHODS Clinically(More)