Mauro S G Pavão

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Brain-specific chondroitin sulfate (CS) proteoglycan (PG) DSD-1-PG/6B4-PG/phosphacan isolated from neonatal mouse brains exhibits neurite outgrowth-promoting activity toward embryonic rat and mouse hippocampal neurons in vitro through the so-called DSD-1 epitope embedded in its glycosaminoglycan side chains. Oversulfated CS variants, CS-D from shark(More)
Oversulfated chondroitin sulfate (CS), dermatan sulfate (DS), and CS/DS hybrid structures bind growth factors, promote the neurite outgrowth of hippocampal neurons in vitro, and have been implicated in the development of the brain. To investigate the expression of functional oversulfated DS structures in the brain, a novel monoclonal antibody (mAb), 2A12,(More)
BACKGROUND Previously, we have reported the presence of highly sulfated dermatans in solitary ascidians from the orders Phlebobranchia (Phallusia nigra) and Stolidobranchia (Halocynthia pyriformis and Styela plicata). Despite the identical disaccharide backbone, consisting of [→4IdoA(2S)β-1→3GalNAcβ-1→], those polymers differ in the position of sulfation on(More)
Correction: Dermatan sulfate in tunicate phylogeny: Order-specific sulfation pattern and the effect of [®4IdoA(2-Sulfate)b-1®3GalNAc (4-Sulfate)b-1®] motifs in dermatan sulfate on heparin cofactor II activity Abstract After the publication of the work entitled " Dermatan sulfate in tunicate phylogeny: Order-specific sulfation pattern and the effect of(More)
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