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  • Angelo D. Favia, Damien Habrant, +8 authors Marco De Vivo
  • Medicine, Chemistry
  • Journal of medicinal chemistry
  • 2012 (First Published: 25 October 2012)
  • Pain and inflammation are major therapeutic areas for drug discovery. Current drugs for these pathologies have limited efficacy, however, and often cause a number of unwanted side effects. In theContinue Reading
  • Stefano Ponzano, Fabio Bertozzi, +13 authors Tiziano Bandiera
  • Medicine, Chemistry
  • Journal of medicinal chemistry
  • 2013 (First Published: 12 September 2013)
  • N-Acylethanolamine acid amidase (NAAA) is a lysosomal cysteine hydrolase involved in the degradation of saturated and monounsaturated fatty acid ethanolamides (FAEs), a family of endogenous lipidContinue Reading
  • Romina Vitale, Giuliana Ottonello, +9 authors Fabio Bertozzi
  • Medicine, Chemistry
  • ChemMedChem
  • 2014 (First Published: 1 February 2014)
  • N-Acylethanolamine acid amidase (NAAA) is a cysteine amidase that preferentially hydrolyzes saturated or monounsaturated fatty acid ethanolamides (FAEs), such as palmitoylethanolamide (PEA) andContinue Reading