Maurizio Podda

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A 15-year-old boy developed contact dermatitis after a foot injury treated with diclofenac. Two years later he ingested diclofenac p.o. for pain relief after exercise. The following day he showed a generalized eczema, fading away during the next two weeks. Subsequently paraceta-mol was well tolerated but had no sufficient analgetic effect. Patch testing was(More)
Induction of a freeze lesion in human skin is an experimental model of hyperalgesia that allows assessing the antihyperalgesic effects of traditional non-steroidal anti-inflammatory drugs (NSAIDs). We have investigated whether this model is also sensitive to selective cyclooxygenase (COX)-2 inhibitors and have characterized morphological substrates of the(More)
The increasing application of charged particles in radiotherapy requires a deeper understanding of early and late side effects occurring in skin, which is exposed in all radiation treatments. We measured cellular and molecular changes related to the early inflammatory response of human skin irradiated with carbon ions, in particular cell death induction and(More)
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