Mauricio S. Caetano

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Tumor cells produce various cytokines and chemokines that attract leukocytes. Leukocytes can amplify parenchymal innate immune responses, and have been shown to contribute to tumor promotion. Neutrophils are among the first cells to arrive at sites of inflammation, and the increased number of tumor-associated neutrophils is linked to poorer outcome in(More)
expression. Bone marrow-derived macrophages from Stat3-sufficient (blue histograms) and hematopoietic Stat3-deficient mice (red histograms) were stained with antibodies specific for the osteoclast/macrophage proteins CD11b, F4/80, M-CSFR and RANK and analyzed by flow cytometry. A representative experiment (1 of 3) is shown. Isotype control is indicated(More)
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