Maurice A Kibel

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SETTING Limited data are available on the characteristics of tuberculosis (TB) disease in young children, especially in high-burden countries. OBJECTIVE To assess the incidence and severity of TB in children aged <5 years. METHODS TB records and chest radiographs of children born in Cape Town in 1999 and diagnosed with TB between 1999 and 2004 were(More)
This is a retrospective review of the clinical, radiologic and laboratory features of 94 cases of childhood miliary tuberculosis seen during a 5-year period, 1985 to 1989. A history of Bacillus Calmette-Guérin vaccination was documented in 88% of children. The median age at presentation was 10.5 months, 52% of cases occurring in those younger than 1 year.(More)
This study aimed to determine the blood lead distributions among young children in the lead mining town of Aggeneys in South Africa's Northern Cape Province, and in the comparison community of Pella, about 40 Km away. A further objective of the study was to explore factors associated with elevated blood lead levels. Children aged between 6 and 10 years(More)
This study evaluated whether different bacillus Calmette-Guérin (BCG) strains, routes of administration, vaccination age and percutaneous tools influenced immune responses to BCG vaccination in infants. Proliferative responses, cytokine production and cell-mediated cytotoxicity obtained in post-vaccinated children were compared to baseline cord bloods and(More)
In recent years higher incidence rates of tuberculosis (TB) have been reported from the Western Cape than from other health regions of South Africa. In contrast to the various pulmonary forms of tuberculosis, tuberculous meningitis (TBM) always requires hospital admission, and can thus be used as an indicator of the extent of the infection in a community,(More)
Blood lead levels were assessed in 293 children aged between 4 and 6 years attending preschool centres in metropolitan Cape Town in order to establish the degree of lead absorption. Anthropometric data, blood count, zinc protoporphyrin and blood lead level were obtained for each child. A questionnaire was used to determine socio-economic status, dietary(More)
Scalp scrapings were collected from 651 children in the Cape Peninsula and along the Western Cape coast to determine which dermatophytic fungi occur in these areas. Fungi were isolated from 61% of specimens, by far the commonest being Trichophyton violaceum. Only half of these specimens showed fungal elements on direct microscopy. Among patients with scaly(More)
BACKGROUND Treating childhood tuberculosis places a large burden on health services, and ways of lessening this were sought. METHODS A randomized controlled trial was conducted to determine the effectiveness of fully intermittent twice weekly treatment for intrathoracic childhood tuberculosis and its effect on adherence to treatment, in comparison with(More)