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  • Garrett M. Frampton, Alex M. Fichtenholtz, +42 authors Roman Yelensky
  • Medicine, Biology
  • Nature Biotechnology
  • 2013 (First Publication: 1 November 2013)
  • As more clinically relevant cancer genes are identified, comprehensive diagnostic approaches are needed to match patients to therapies, raising the challenge of optimization and analytical validationContinue Reading
  • Maureen T. Cronin, Mylan Pho, +5 authors Joffre B. Baker
  • Biology, Medicine
  • The American journal of pathology
  • 2004
  • Throughout the last decade many laboratories have shown that mRNA levels in formalin-fixed and paraffin-embedded (FPE) tissue specimens can be quantified by reverse transcriptase-polymerase chainContinue Reading
  • Maureen T. Cronin, Chithra Sangli, +7 authors Drew Watson
  • Medicine
  • Clinical chemistry
  • 2007 (First Publication: 19 April 2007)
  • BACKGROUND Oncotype DX is a clinically validated, high-complexity, multianalyte reverse transcription-PCR genomic test that predicts the likelihood of breast cancer recurrence in early-stage,Continue Reading
  • Nir Peled, Gary Palmer, +10 authors Vincent A. Miller
  • Biology, Medicine
  • Journal of thoracic oncology : official…
  • 2012 (First Publication: 1 September 2012)
  • The echinoderm microtubule-associated protein-like 4-anaplastic lymphoma kinase (EML4-ALK) gene fusion occurs in 2–7% of NSCLC cases[1,2] and is typically identified by Vysis ALK Break-ApartContinue Reading