Varieties of Living Things: Life at the Intersection of Lineage and Metabolism
The central argument is that life arises when lineage-forming entities collaborate in metabolism, and the view of life as a continuum of variably structured collaborative systems leaves open the possibility that a variety of forms of organized matter might be usefully understood as living entities.
Do simple models lead to generality in ecology?
Prokaryotic evolution and the tree of life are two different things
This article sets out alternative models to the tree of life to study prokaryote-eukaryote evolution, surmising that phylogeny opted for a single model as a holdover from the Modern Synthesis of evolution.
Fundamental issues in systems biology.
It is suggested that resolving basic problems is a key task for successful systems biology, and that philosophers could contribute to its realisation, and an argument for more sociologically informed collaboration between scientists and philosophers is concluded.
Knowledge-making distinctions in synthetic biology.
It is suggested that all these knowledge-making distinctions in synthetic biology raise fundamental questions about the nature of biological investigation and its relationship to the construction of biological components and systems.
The roles of integration in molecular systems biology.
Size doesn’t matter: towards a more inclusive philosophy of biology
It is suggested that taking more notice of microbes will transform some of the philosophy of biology’s standard ideas on ontology, evolution, taxonomy and biodiversity and break down conventional thinking that microbes are solely or primarily single-celled organisms.
Endosymbiosis and its implications for evolutionary theory
- Maureen A. O’Malley
- Biology, PsychologyProceedings of the National Academy of Sciences
- 16 April 2015
How metabolic innovations associated with endosymbioses can drive evolution and thus provide an explanatory account of important episodes in the history of life is discussed.
Microbiota-gut-brain research: A critical analysis
- Katarzyna B Hooks, J. Konsman, Maureen A. O’Malley
- PsychologyBehavioral and Brain Sciences
- 12 September 2018
Examining critically the core practices and findings of experimental MGB research are examined to raise questions about them for brain and behavioural scientists who may not be familiar with the field and to challenge the way in which MGB findings are presented.
Disciplinary baptisms: a comparison of the naming stories of genetics, molecular biology, genomics, and systems biology.
- Alexander Powell, Maureen A. O’Malley, S. Müller-Wille, J. Calvert, J. Dupré
- ArtHistory and Philosophy of the Life Sciences
This work compares two recently formed disciplines, systems biology and genomics, with two earlier related life sciences, genetics and molecular biology, and outlines how the establishment of each discipline relies upon an interplay of factors that include paradigmatic achievements, technological innovation, and social formations.