Mattijs de Groot

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Forty-nine patients with Type I diabetes mellitus were assessed to examine the relationship between lifetime prevalence of psychiatric illness and retinopathy severity. The subjects with a history of psychiatric illness had significantly worse retinopathy than the subjects without psychiatric illness. Eighty-nine percent of the subjects with severe(More)
Three-dimensional high-resolution imaging methods are important for cellular-level research. Optical coherence microscopy (OCM) is a low-coherence-based interferometry technology for cellular imaging with both high axial and lateral resolution. Using a high-numerical-aperture objective, OCM normally has a shallow depth of field and requires scanning the(More)
In polarization-sensitive optical coherence tomography (PS-OCT) the use of single-mode fibers causes unpredictable polarization distortions which can result in increased noise levels and erroneous changes in calculated polarization parameters. In the current paper this problem is addressed by a new Jones matrix analysis method that measures and corrects(More)
  • Jianhua Mo, Mattijs De Groot, Johannes F De Boer, E D A Huang, C P Swanson, J S Lin +111 others
  • 2013
We present a novel method to extend the depth-of-focus of Optical Coherence Tomography (OCT). OCT is an interferometric imaging technique that provides depth-resolved scattering information. The axial resolution in OCT is provided by the coherence gate and is invariant over the full image depth. The lateral resolution is determined by the beam parameters(More)
We present a new method for high-resolution, three-dimensional fluorescence imaging. In contrast to beam-scanning confocal microscopy, where the laser focus must be scanned both laterally and axially to collect a volume, we obtain depth information without the necessity of depth scanning. In this method, the emitted fluorescence is collected in the backward(More)
  • De Jong, T E C Nijsten, R J Borgonjen, Van Cranenburgh, Van Deutekom, J J E Van Everdingen +27 others
  • 2016
Please be advised that this information was generated on 2016-11-25 and may be subject to change. eScholarship provides open access, scholarly publishing services to the University of California and delivers a dynamic research platform to scholars worldwide. Local Identifier: doj_21769 eScholarship provides open access, scholarly publishing services to the(More)
PURPOSE At present, the only approved fluorescent tracer for clinical near-infrared fluorescence-guided sentinel node (SN) detection is indocyanine green (ICG), but the use of this tracer is limited due to its poor retention in the SN resulting in the detection of higher tier nodes. We describe the development and characterization of a next-generation(More)
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