Mattia Rocco

Emre Brookes3
Barbara Cardinali2
Fabio Ferri2
Patrice Vachette2
3Emre Brookes
2Barbara Cardinali
2Fabio Ferri
2Patrice Vachette
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Progress in analytical ultracentrifugation (AUC) has been hindered by obstructions to hardware innovation and by software incompatibility. In this paper, we announce and outline the Open AUC Project. The goals of the Open AUC Project are to stimulate AUC innovation by improving instrumentation, detectors, acquisition and analysis software, and collaborative(More)
Figure S1 Panel A, the renewed GUI of the US-SOMO SAS module main panel. In the graphics windows, the I(q) vs q and the P(r) vs. r curves, both computed directly from the BSA crystal structure 4F5S (Bujacz, 2012), using Crysol and the US-SOMO internal P(r)/SAXS method, respectively, are shown. The new GUI of the US-SOMO SAS module is shown in Fig. S1. It is(More)
Hydrodynamic characterisation of (bio)macromolecules is a well-established field. Observables linked to translational friction, such as the translational diffusion (D t 0 (20,w)) and sedimentation ( $$ s_{(20,\text{w})}^{0} $$ s ( 20 , w ) 0 ) coefficients, are the most commonly used parameters. Both can be computed starting from high-resolution structures,(More)
Mass spectrometry (MS) is producing high volumes of data supporting oncological sciences, especially for translational research. Most of related elaborations can be carried out by combining existing tools at different levels, but little is currently available for the automation of the fundamental steps. For the analysis of MALDI/TOF spectra, a number of(More)
The average pore size ξ0 of filamentous networks assembled from biological macromolecules is one of the most important physical parameters affecting their biological functions. Modern optical methods, such as confocal microscopy, can noninvasively image such networks, but extracting a quantitative estimate of ξ0 is a nontrivial task. We present here a fast(More)
UltraScan Solution Modeler (US-SOMO) computes hydrodynamic parameters and small-angle scattering data from biological macromolecular structural representations and compares them with experimental data for structural determination and validation. At XSEDE 12, a GUI integrated gateway was introduced to offload large computations to various HPC resources. The(More)
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