Matthieu Mahévas

Learn More
A large number of auto-immune diseases are treated with rituximab, an antibody against CD20 that depletes most of the B-cells in the organism. The response to this treatment depends largely on the disease and the type of lymphoid cells involved in the auto-immune process. We recently reported that B-cell depletion in immune thrombocytopenia induced the(More)
BACKGROUND The association between sarcoidosis and glomerular diseases has not been extensively investigated in a large series and the potential features of this uncommon association remain to be determined. METHODS We retrospectively identified 26 patients with biopsy-proven glomerular lesions that occurred in a sarcoidosis context. Potential remission(More)
Abbreviations CVID Common variable immunodeficiency disorders SNP Single nucleotide polymorphism TNFA Tumor necrosis factor alpha BTNL2 Butyrophilin-like 2 ANXA11 Annexin A11 HC Healthy control DNA Deoxyribonucleic acid T Reg Regulatory T cell Common Variable Immunodeficiency Disorders (CVID) are a group of heterogeneous disorders defined by antibody(More)
The recent large decrease in splenectomy use for chronic immune thrombocytopenia (ITP) is partly due to still-unsolved questions about long-term safety. We performed the first single-center exposed/unexposed cohort study evaluating the long-term incidence of splenectomy complications in patients with primary ITP. Overall, 83 patients who underwent(More)
  • 1