Matthias Thöny

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An important mechanism by which macrophages (M phi) halt the growth of and eliminate a broad array of intracellular pathogens is the production of nitric oxide (NO). NO generation is catalyzed by inducible nitric oxide synthase (iNOS) converting arginine into citrulline and NO. In murine M phi, iNOS activity is regulated largely at the transcriptional(More)
Bovine monocytes and monocyte-derived macrophages (MDM) activated by various means were assessed for induction of inducible nitric oxide synthase (iNOS), using the Griess assay, Northern blotting and reverse transcription/polymerase chain reaction (RT-PCR). Interferon-gamma (IFN-gamma) induced little, if any, iNOS expression and NO production in MDM,(More)
We assessed bovine bone marrow-derived macrophages and monocyte-derived macrophages for expression of inducible nitric oxide synthase (iNOS) activity. Both cell types expressed iNOS activity upon stimulation with Salmonella dublin (S. dublin) or with LPS. A 372-bp fragment of the bovine iNOS mRNA could be amplified by reverse transcription-PCR from mRNA of(More)
Interactive rendering of large scale vector maps is a key challenge for high-quality geographic visualization software systems. In this paper we present a novel approach for the visualization of large scale vector maps over detailed height-field terrains. Our method uses a deferred line shading approach to render large scale vector maps directly in a(More)
Terrain rendering is widely used in industry and research. GIS software packages as well as navigation systems make use of terrain rendering to visualize terrain information. Recent trends in research show that scientific terrain visualization is shifting more and more to an interactive analysis tool. This allows domain specific users to perform visual(More)
A common source of challenges in geographic visualisation systems is the growing amount of available data. Datasets containing different information need to be merged and analysed under a common context. For some purposes these datasets can interact intelligently and append additional information to a scientific visualisation. In this research proposal, we(More)
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