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  • Werner Schroth, Lydia Antoniadou, +6 authors Hiltrud Brauch
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2007 (First Publication: 20 November 2007)
  • PURPOSE The clinical outcome of tamoxifen-treated breast cancer patients may be influenced by the activity of cytochrome P450 enzymes that catalyze the formation of antiestrogenic metabolitesContinue Reading
  • Heather Ribaudo, Hanying Liu, +11 authors David W. Haas
  • Medicine
  • The Journal of infectious diseases
  • 2010 (First Publication: 1 September 2010)
  • In AIDS Clinical Trials Group protocols 384, A5095, and A5097s, we characterized relationships between 22 polymorphisms in CYP2B6, ABCB1, and CYP3A5; plasma efavirenz exposure; and/or treatmentContinue Reading
  • Dan Rosmarin, Claire Palles, +41 authors Ian Tomlinson
  • Medicine
  • Journal of clinical oncology : official journal…
  • 2014 (First Publication: 1 April 2014)
  • PURPOSE Fluourouracil (FU) is a mainstay of chemotherapy, although toxicities are common. Genetic biomarkers have been used to predict these adverse events, but their utility is uncertain. PATIENTSContinue Reading
  • Ghazaleh Darmani, Carl M. Zipser, +5 authors Ulf Ziemann
  • Medicine, Biology
  • The Journal of Neuroscience
  • 2016 (First Publication: 7 December 2016)
  • Alpha-5 gamma-aminobutyric acid type A receptors (α5-GABAARs) are located extrasynaptically, regulate neuronal excitability through tonic inhibition, and are fundamentally important for processesContinue Reading
  • Lucas Actis-Goretta, Antoine Lévèques, +7 authors Gary Williamson
  • Chemistry, Medicine
  • The American journal of clinical nutrition
  • 2013 (First Publication: 1 October 2013)
  • BACKGROUND (-)-Epicatechin is a dietary flavonoid present in many foods that affects vascular function, but its action is limited by incomplete absorption, conjugation, and metabolism. Factors thatContinue Reading