Learn More
This article deals with inconsistency of relative, rather than absolute, treatment effects in binary/dichotomous outcomes. A body of evidence is not rated up in quality if studies yield consistent results, but may be rated down in quality if inconsistent. Criteria for evaluating consistency include similarity of point estimates, extent of overlap of(More)
Direct evidence comes from research that directly compares the interventions in which we are interested when applied to the populations in which we are interested and measures outcomes important to patients. Evidence can be indirect in one of four ways. First, patients may differ from those of interest (the term applicability is often used for this form of(More)
GRADE requires a clear specification of the relevant setting, population, intervention, and comparator. It also requires specification of all important outcomes - whether evidence from research studies is, or is not, available. For a particular management question, the population, intervention, and outcome should be sufficiently similar across studies so(More)
OBJECTIVES To provide an overview of the development of health technology assessment (HTA) in Germany since the 1990s. METHODS Analysis of key documents (e.g. literature, laws, and other official documentation) and personal experiences. RESULTS Health technology assessment (HTA) entered the political agenda in Germany only in the mid-1990s, basically as(More)
To the Editor: We want to comment on the study by Martelli et al. in Volume 23:4, which appears to have several mistakes and seems to be outdated and probably biased. Several agencies mentioned in the study now have different tasks and mandates and accordingly have different denominations. The CCOHTA for example has been renamed CADTH (Canadian Agency for(More)
  • 1