Matthias Laengin

Learn More
BACKGROUND Artesunate-amodiaquine combination for the treatment of childhood malaria is one of the artemisinin combination therapies (ACTs) recommended by National authorities in many African countries today. Effectiveness data on this combination in young children is scarce. METHODS The effectiveness of three daily doses of artesunate plus amodiaquine(More)
BACKGROUND Diligent and correct laboratory diagnosis and up-front identification of risk factors for progression to severe disease are the basis for optimal management of malaria. METHODS Febrile children presenting to the Medical Research Unit at the Albert Schweitzer Hospital (HAS) in Lambaréné, Gabon, were assessed for malaria. Giemsa-stained thick(More)
BACKGROUND Detection of malaria pigment (or haemozoin; Hz)-containing leukocytes may have prognostic relevance in malaria; however, studies reported conflicting results, with microscopic counts suggestive of being inaccurate and imprecise. METHODS Numbers of Hz-containing leukocytes from a malaria patient obtained with a flow cytometer counting 50.000(More)
  • 1