Matthias L. Schroeter

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Aging reduces cerebral blood flow in association cortices during rest. However, the influence of age on functional brain activation is still controversial. The aim of our study was to examine age dependency of brain activation in primary and association cortices. Therefore, changes in the concentration of oxy- and deoxyhemoglobin as well as changes in the(More)
Although it is well known that executive processes supported by the frontal lobe develop during childhood and adolescence, only one functional imaging study has used the Stroop task to investigate the relationship between frontal lobe function and cognition from a developmental point of view. Hence, we measured brain activation in the lateral prefrontal(More)
BACKGROUND Peripheral brain-derived neurotrophic factor (BDNF) is decreased in acute major depressive disorder (MDD) and bipolar disorder (BD) and recovered after treatment. Here we validated on a meta-analytical level whether BDNF restores differentially according to treatment response and whose measurements could be used as a biomarker, plasma or serum.(More)
BACKGROUND Depression has a lifetime prevalence of up to 20%. Neuroimaging methods have revealed various structural and functional changes that occur in a human brain during a depressive episode. However, we still lack information concerning the extent to which structural and functional changes co-occur in a depressed brain. Furthermore, it is difficult to(More)
In a Stroop interference task, subjects are required to name the color of a word, while ignoring the meaning of the word. The increase in time taken to name the color name if the underlying word is incongruent to the color is called Stroop color-word interference effect. With increasing age, reaction time (RT) is slowed. In an functional magnetic resonance(More)
Functional near-infrared spectroscopy (fNIRS) allows the ability to monitor brain activation by measuring changes in the concentration of oxy- and deoxy-hemoglobin. Until now no standardized approach for fNIRS data analysis has been established, although this has to be regarded as a precondition for future application. Hence, we applied the well-established(More)
OBJECTIVE Frontotemporal dementia is the most common form of frontotemporal lobar degeneration. It is characterized by deep alterations in behavior and personality. We conducted a systematic and quantitative meta-analysis to examine its neural correlates and place the disease in a framework of cognitive neuropsychiatry. METHODS MedLine and Current(More)
Frontotemporal lobar degeneration is the second most common diagnosis of dementia in individuals younger than 65 years. We conducted a systematic and quantitative meta-analysis to examine neural correlates of frontotemporal lobar degeneration and its subtypes and to place the disease in a framework of cognitive neuropsychiatry. MedLine and Current Contents(More)
Elevated blood levels of S100B in neuropsychiatric disorders have so far been mainly attributed to glial pathologies. However, increases or dysfunction of adipose tissue may be alternatively responsible. Our study assessed S100B serum levels in 60 adult subjects without a prior history of neuropsychiatric disorders. S100B concentrations were closely(More)
Alzheimer's disease is the most common form of dementia. Its prodromal stage amnestic mild cognitive impairment is characterized by deficits of anterograde episodic memory. The development of standardized imaging inclusion criteria has to be regarded as a prerequisite for future diagnostic systems. Moreover, successful treatment requires isolating imaging(More)