Matthias Klar

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In mammals, the essential neuronal substrate for the generation of the horizontal optokinetic nystagmus (hOKN) are the nucleus of optical tract (NOT) and the dorsal terminal nucleus (DTN). The medial terminal nucleus (MTN) is thought to be involved in vertical OKN control. Characteristic for all of these neurons is a high-direction selectivity. Although(More)
Cannabinoids are known to inhibit neurotransmitter release in the CNS through CB1 receptors. The present study compares the effects of synthetic cannabinoids on acetylcholine (ACh) release in human and mice neocortex. We further investigated a possible endocannabinoid tone on CB1 receptors in human neocortex caused by endogenous agonists like anandamide or(More)
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