Learn More
We examine the impact of the loss recovery mechanism on the performance of a reliable multicast protocol. Approaches to reliable multicast can be divided into two major classes: source-based recovery, and distributed recovery. For both classes we consider the state of the art: For source-based recovery, a type 2 hybrid ARQ scheme with parity retransmission.(More)
Chondrocytes are important for the development and maintenance of articular cartilage. However, both in osteoarthritis (OA) and rheumatoid arthritis (RA) chondrocytes are involved in the process of cartilage degradation and synthesize important immunomodulatory mediators, including nitric oxide (NO) generated by the inducible NO synthase (iNOS). To uncover(More)
PURPOSE Aqueous tear deficiency due to lacrimal gland insufficiency is one of the major causes of dry eye disease. In severe cases, such as Sjogren's syndrome, Stevens-Johnson syndrome, or ocular cicatricial pemphigoid, therapy with artificial tears is often insufficient to relieve severe discomfort, prevent progressive ocular surface disease, or enable(More)
We investigate reliable multicast communication over satellite networks. We compare a scenario where receivers can use a feedback channel to signal loss to a scenario where no feedback channel is available. We show that the introduction of a feedback channel is the key to allow for bandwidth-eecient, robust, and fully reliable multicast communication via(More)
This paper presents JChannels , a framework to support the implementation of network protocols in Java. The goals of JChannels are the rapid development of structured, reusable, and configurable protocol stacks profiting from Java features like incorporate concurrency, portability, and runtime class loading. We present the JChannels architecture show how to(More)
Pluripotency is characterized by specific transcription factors such as OCT4, NANOG, and SOX2, but also by pluripotency-associated microRNAs (miRs). Somatic cells can be reprogrammed by forced expression of these factors leading to induced pluripotent stem cells (iPSCs) with characteristics similar to embryonic stem cells (ESCs). However, current(More)
We investigate reliable multicast communication over satellite networks. We compare a scenario where receivers can use a feedback channel to signal loss to a scenario where no feedback channel is available. We show that the introduction of a feedback channel is the key to allow for bandwidth-e cient, robust, and fully reliable multicast communication via(More)
We present a system of architectural design patterns for the implementation of flexible, extensible, and maintainable application tailored network protocol software in end-systems. The pattern system mainly follows a vertical structuring approach. Outsourced De-Multiplexing reduces cross-talk between different protocol sessions. Data-Path Reification(More)
We show how layering in communication software violates the principle of separating concerns. Examples illustrate that layering couples receiver-and sender functions, sharing message headers among layers creates dependencies between layers that largely compromise re-usability, QoS management is scattered over all layers, and layers are tightly coupled with(More)