Matthias Jacobi

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The functional anatomy of the knee is frequently studied but remains incompletely understood. Numerous authors have described a structure in the lateral knee connecting the lateral femoral condyle with the lateral meniscus and tibial plateau. The goal of this study is to define the incidence, anatomy, and histology of this structure, the anterolateral(More)
We investigated the role of a functional brace worn for four months in the treatment of patients with an acute isolated tear of the posterior cruciate ligament to determine whether reduction of the posterior tibial translation during the healing period would give an improved final position of the tibia. The initial and follow-up stability was tested by(More)
Varisation osteotomies on the distal femur are an established treatment method for valgus osteoarthritis of the knee in younger patients. Osteotomy can be done in a lateral open-wedge or medial closed-wedge manner. We retrospectively studied 14 patients treated by the lateral open-wedge technique, fixed with the Tomofix plate, with a mean duration of(More)
Osteoathritis (OA) of the knee is common, and the chances of suffering from OA increase with age. Its treatment should be initially nonoperative-and requires both pharmacological and nonpharmacological treatment modalities. If conservative therapy fails, surgery should be considered. Surgical treatments for knee OA include arthroscopy, cartilage repair,(More)
High tibial open wedge valgisation osteotomy (HTO) is a widely used procedure for the treatment of unicompartimental osteoarthritis of the knee. Instead of the classical paramedian longitudinal skin incision, some advocate an oblique incision, in order to get a better exposure of the postero-medial aspect of the tibial head, while reducing strain on the(More)
The purpose of this study is to evaluate clinical and radiological outcomes of patients treated with autologous matrix-induced chondrogenesis (AMIC) for full-thickness chondral and osteochondral defects of the femoral condyles and patella. A retrospective evaluation of clinical and radiographic outcomes of patients treated with AMIC for chondral and(More)
Osteoset® T is a calcium sulphate void filler containing 4% tobramycin sulphate, used to treat bone and soft tissue infections. Despite systemic exposure to the antibiotic, there are no pharmacokinetic studies in humans published so far. Based on the observations made in our patients, a model predicting tobramycin serum levels and evaluating their toxicity(More)
Closing wedge high tibial osteotomy is an efficient method for the treatment of medial osteoarthritis of the knee. Prerequisites of successful surgery are proper indication and planning as well as the understanding of biomechanics and pathophysiology. The technique of osteotomy to choose (opening or closing wedge) depends on the type of malalignment and on(More)
Four hundred fifty sperm complements from eight controls were analyzed. A conservative estimate of aneuploidy was 1.8% with a hyperhaploid rate of 0.9% (4/450). The overall frequency of structural aberrations was 8.9% (40/450). The proportion of X-bearing (47.5%) and Y-bearing (52.5%) sperm did not differ significantly. Sperm complements were analyzed from(More)
High tibial osteotomy is a well-established method for the treatment of medial unicompartmental osteoarthritis of the knee. We analysed retrospectively the long-term outcome of open and closing wedge valgisation high tibial osteotomies. Out of 71 patients, 54 (76%) were available for the study. Survival rates and the influence of the osteotomy type were(More)