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Inhibition of intrinsic protein tyrosine kinase activity of EGF-receptor kinase complex from human breast cancer cells by the marine sponge metabolite (+)-aeroplysinin-1.

• Matthias Heinrich Kreuter, R. E. Leake, +4 authors H. Schröder
• Comparative biochemistry and physiology. B…
• 1990

1. (+)-Aeroplysinin-1, a naturally occurring tyrosine metabolite from the marine sponge Verongia aerophoba, was found to inhibit the phosphorylation of lipocortin-like proteins by a highly purified… (More)

Bioactivity of well-defined green tea extracts in multicellular tumor spheroids.

• Wolfgang F. Mueller-Klieser, S Schreiber-Klais, Stefan Walenta, Matthias Heinrich Kreuter
• International journal of oncology
• 2002

The effect of green tea extracts (GTE) of a reproducible, well-defined composition on cellular viability, proliferation, and antioxidant defense was investigated in multicellular spheroids derived… (More)

Vitex agnus-castus

• Beat H Meier, Caroline Allemann, Matthias Heinrich Kreuter
• 2005

Vitex agnus-castus has a long tradition as a herbal remedy and was used in ancient times not only as an anaphrodisiac and for preserving chastity but also against diverse disturbances of the female… (More)

Piper cubeba targets multiple aspects of the androgen-signalling pathway. A potential phytotherapy against prostate cancer growth?

• Jianying Yam, Matthias Heinrich Kreuter, Juergen Drewe
• Planta medica
• 2008

Despite the high prevalence of prostate cancer (PC) in the Western world, there is a dearth of effective medication. Since the androgen-signalling pathway is very much involved in PC growth and… (More)

Production of the cytostatic agent aeroplysinin by the sponge Verongia aerophoba in in vitro culture.

• Matthias Heinrich Kreuter, Andrea A Robitzki, +6 authors Werner E G Müller
• Comparative biochemistry and physiology. C…
• 1992

1. The marine sponge Verongia aerophoba contains two bioactive secondary metabolites from tyrosine, (+)-aeroplysinin-1 [3',5'-dibromo-1',2'-dihydroxy-4'-… (More)

Role of phospholipase A2 in the stimulation of sponge cell proliferation by homologous lectin.

• Monika Gramzow, H. Schröder, +6 authors Werner E G Müller
• Cell
• 1989

Using the Geodia cydonium system, we showed that after incubation of competent sponge cells in the presence of lectin, phospholipase A2 was released from the cells. The substrates for this enzyme,… (More)

The D-mannose-specific lectin from Gerardia savaglia blocks binding of human immunodeficiency virus type I to H9 cells and human lymphocytes in vitro.

• Werner E G Müller, K. Renneisen, Matthias Heinrich Kreuter, H. Schröder, Ilan Winkler
• Journal of acquired immune deficiency syndromes
• 1988

The new D-mannose-specific lectin from Gerardia savaglia is shown to prevent infection of H9 cells with human immunodeficiency virus type 1 (HIV-1; strain HTLV-IIIB). At a concentration of 0.2… (More)

Echinacea purpurea Protects Against Restraint Stress-Induced Immunosuppression in BALB/c Mice.

• Seonyoung Park, Mak-Soon Lee, +7 authors Yangha Kim
• Journal of medicinal food
• 2017

Echinacea purpurea has been widely used for the prevention and treatment of upper respiratory tract infections and the common cold. The restraint stress has been reported to suppress a broad spectrum… (More)

Sulphoevernan, a polyanionic polysaccharide, and the narcissus lectin potently inhibit human immunodeficiency virus infection by binding to viral envelope protein.

• Betty Weiler, H. Schröder, +7 authors Werner E G Müller
• The Journal of general virology
• 1990

Sulphoevernan is a sulphated alpha-1----3, 1----4 polyglucan (Mr 20,000) with a helical structure. This compound effectively inhibits both human immunodeficiency virus type 1 (HIV-1) and type 2… (More)

Inhibitory activity of a green tea extract and some of its constituents on multidrug resistance-associated protein 2 functionality.

• Matthias Netsch, Heike Gutmann, +4 authors J. Anne Drewe
• Planta medica
• 2005

Green tea extracts (GTE) might modulate ABC transporter gene expression or function. This may be relevant in the treatment of cancer or in influencing intestinal drug permeability. To gain more… (More)

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