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We report principal component analysis (PCA) of (1)H NMR spectra recorded for a group of human lung carcinoma cell lines in culture and (1)H NMR analysis of extracts from the same samples. The samples studied were cells of lung tumour origin with different chemotherapy drug resistance patterns. For whole cells, it was found that the statistically(More)
We report the successful classification, by artificial neural networks (ANNs), of (1)H NMR spectroscopic data recorded on whole-cell culture samples of four different lung carcinoma cell lines, which display different drug resistance patterns. The robustness of the approach was demonstrated by its ability to classify the cell line correctly in 100% of(More)
In complex medical devices, many features are realized by software. As these devices are safety-critical, the healthcare industry has to ensure a high quality of their products. Today, the system requirements are usually specified in form of use cases using natural language. Whether the developed systems fulfill those requirements is verified by testing.(More)
a r t i c l e i n f o a b s t r a c t The elemental composition of Mercury's surface, which has been recently measured by the NASA MErcury Surface, Space ENvironment, GEochemistry, and Ranging (MESSENGER) spacecraft, suggests a mineralogy dominated by magnesium-rich orthopyroxene and feldspar. The most magnesium-rich and aluminium-poor regions of Mercury's(More)
We report the successful classification, by artificial neural networks (ANNs), of 1 H NMR spectroscopic data recorded on whole-cell culture samples of four different lung carcinoma cell lines, which display different drug resistance patterns. The robustness of the approach was demonstrated by its ability to classify the cell line correctly in 100% of cases,(More)
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