Matthias Fischer

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Though most dermatoses are not life-threatening, skin diseases play an important role in intensive care medicine. Skin findings in intensive care patients may reflect the underlying disease or be complications of intensive medical care. Most important are drug reactions, infections, bacterial toxin reactions, erythroderma, ANCA-positive vasculitides (such(More)
The hand-foot syndrome (HFS) (palmoplantar erythrodysesthesia) designates acute, painful erythemas of the palms and soles of the feet caused by antineoplastic chemotherapies. The most frequent trigger substances are 5-fluoruracil and its derivates. At maximum severity, the HFS is bullous to erosive or ulcerous in character. The pathogenesis has not yet been(More)
BACKGROUND Dermatology and venereology, as a cross-sectional discipline, plays an important role in the interdisciplinary care of inpatients. Nonetheless, only a few studies on dermatological consultations have been performed. We reviewed the dermatological consulting service at the University Hospital of the Martin-Luther-University, Halle, Germany. (More)
In this report, we develop a cost model for the communication time on parallel computers consisting of processors and a service network, i.e., a network performing services like broadcast, synchronization, and global variables. Because we do not have a parallel computer at our disposal that is equipped with a service network, we emulate the service network(More)
Ionotrope glutamate receptors of the N-methyl-d-aspartate (NMDA) receptor type are expressed on keratinocytes and influence the intracellular calcium concentration. The importance of NMDA receptors in pathophysiological processes in the skin is, however, still unclear. Epidermal distribution patterns of NMDA receptors were investigated in dermatoses with(More)
Livedoid vasculopathy (LV) is characterized by localized painful ulcers, livedo reticularis and atrophie blanche. LV is considered as an occlusive vasculopathy due to a hypercoagulable state. Hyperhomocysteinemia is a prothrombotic condition, which has as yet received little attention in this context. We report a 49-year-old woman with livedoid(More)
In the present study, the distribution of ionotropic glutamate receptors of the N-methyl-D-aspartate (NMDA)-receptor type was immunohistochemically demonstrated in healthy human skin (n = 22) and healthy buccal mucosa (n = 20). Moreover, the intracellular calcium concentration of HaCaT-cells and native human keratinocytes were studied under the influence of(More)