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UNLABELLED Several factors have to be considered for implementing an accurate attenuation-correction (AC) method in a combined MR-PET scanner. In this work, some of these challenges were investigated, and an AC method based entirely on the MRI data obtained with a single dedicated sequence was developed and used for neurologic studies performed with the(More)
Positron emission tomographs (PETs) are currently almost exclusively designed as hybrid systems. The current standard is the PET/CT combination, while prototype PET/MRI systems are being studied by several research groups. One problem in these systems is that the transaxial field-of-view of the second system is smaller than that of the PET camera and does(More)
UNLABELLED In routine whole-body PET/MR hybrid imaging, attenuation correction (AC) is usually performed by segmentation methods based on a Dixon MR sequence providing up to 4 different tissue classes. Because of the lack of bone information with the Dixon-based MR sequence, bone is currently considered as soft tissue. Thus, the aim of this study was to(More)
We present a method for fast and automatic labeling of anatomical structures in MR FastView localizer images, which can be useful for automatic MR examination planning. FastView is a modern MR protocol, that provides larger planning fields of view than previously available with isotropic 3D resolution by scanning during continuous movement of the patient(More)
PURPOSE In quantitative PET imaging, it is critical to accurately measure and compensate for the attenuation of the photons absorbed in the tissue. While in PET/CT the linear attenuation coefficients can be easily determined from a low-dose CT-based transmission scan, in whole-body MR/PET the computation of the linear attenuation coefficients is based on(More)
In whole-body MR/PET, the human attenuation correction can be based on the MR data. However, an MR-based field-of-view (FoV) is limited due to physical restrictions such as B0 inhomogeneities and gradient nonlinearities. Therefore, for large patients, the MR image and the attenuation map might be truncated and the attenuation correction might be biased. The(More)
UNLABELLED Simultaneous PET/MR of the brain is a promising technology for characterizing patients with suspected cognitive impairment or epilepsy. Unlike CT, however, MR signal intensities do not correlate directly with PET photon attenuation correction (AC), and inaccurate radiotracer SUV estimation can limit future PET/MR clinical applications. We tested(More)
PURPOSE To provide 3D multicontrast anatomical MR with high isotropic resolution and metabolic positron emission tomography (PET) images using a respiratory motion-compensated simultaneous PET-MR examination with high scan efficiency. THEORY AND METHODS Standard abdominal PET-MR examinations combine MR data obtained during multiple breath-holds with(More)
AIM To compare attenuation correction (AC) approaches for positron emission tomography/magnetic resonance imaging (PET/MRI) in clinical neuro-oncology. Methods: Forty-nine PET/MRI brain scans were included: brain tumor studies using 18F-FET (n = 31) and 68-Ga-DOTANOC (n = 7) and studies of healthy subjects using 18F-FDG (n = 11). For each subject, MR-based(More)
PURPOSE 4D-MRI based on resorting of 2D-cine-MRI images shows great potential to assess tumor motion more accurately compared to 4D-CT, however, it suffers from low through-plane resolution and stitching artifacts. 4D-MRI based on 3D acquisition results in stitching-artifact-free images with high in-plane and through-plane resolutions. In this study, we(More)