Matthias David

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OBJECTIVE The purpose of this study was to determine the safety and efficacy of focused ultrasound surgery with magnetic resonance imaging guidance for the noninvasive treatment of uterine leiomyomas. STUDY DESIGN Fifty-five women with clinically significant uterine leiomyomas were treated. Pain and complications were assessed prospectively, and(More)
Purpose Are there differences regarding important perinatal outcome-parameters in Berlin relating to ethnicity? Patients and methods A database was available covering 152,193 single deliveries in all hospitals in Berlin/Germany in the period 1993–1999, including 132,555 German women and 19,638 women of other ethnicities. Comparisons were made between a(More)
OBJECTIVE To report all pregnancies to date after magnetic resonance-guided focused ultrasound surgery (MRgFUS) for the conservative treatment of clinically significant uterine fibroids. DESIGN Prospective registry of all known pregnancies occurring after MRgFUS maintained by the device manufacturer and reported to the Food and Drug Administration. (More)
This study examined whether ARDS patients in whom predefined ventilator settings fail to maintain oxygenation and CO2 removal can be safely transitioned to high-frequency oscillatory ventilation (HFOV), and whether HFOV use is efficacious. Prospective observational study in the 14-bed intensive care unit of a university hospital. 42 patients with ARDS(More)
INTRODUCTION Endotracheal intubation in the ICU is a challenging procedure and is frequently associated with life-threatening complications. The aim of this study was to investigate the effect of the C-MAC® video laryngoscope on laryngeal view and intubation success compared with direct laryngoscopy. METHODS In a single-center, prospective, comparative(More)
OBJECTIVE This review outlines the basic principle, in addition to validated and upcoming clinical use of electrical impedance tomography (EIT). EIT generates functional tomograms of the thorax for detection of changes in regional lung aeration. These images allow an intraindividual comparison of changes in regional lung function. Specifically, EIT aims to(More)
INTRODUCTION The lectin-like domain of TNF-α enhances the fluid clearance across the alveolar barrier. For experimental purposes, the lectin-like domain can be mimicked by a synthetic peptide representing the TIP-motif of TNF-α. The present study aims to assess the acute effect of TIP on the pulmonary function in a porcine model of acute respiratory(More)
STUDY OBJECTIVE To study the dynamics of lung compartments by dynamic CT (dCT) imaging during uninterrupted pressure-controlled ventilation (PCV) and different positive end-expiratory pressure (PEEP) settings in healthy and damaged lungs. DESIGN Experimental animal investigation. SETTING Experimental animal facility of a university department. (More)
OBJECTIVE The objective of the study is to compare outcomes after conservative management alone versus conservative management with cerclage in the treatment of amniotic sac prolapse in the second trimester. STUDY DESIGN Retrospective, comparative study at a university hospital/tertiary referral centre. The medical data was provided by the files of 182(More)
INTRODUCTION Sepsis-associated delirium (SAD) increases morbidity in septic patients and, therefore, factors contributing to SAD should be further characterized. One possible mechanism might be the impairment of cerebrovascular autoregulation (AR) by sepsis, leading to cerebral hypo- or hyperperfusion in these haemodynamically unstable patients. Therefore,(More)