Matthias Christen

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The bacterial second messenger cyclic diguanosine monophosphate (c-di-GMP) regulates cellular motility and the synthesis of organelles and molecules that promote adhesion to a variety of biological and nonbiological surfaces. These properties likely require tight spatial and temporal regulation of c-di-GMP concentration. We have developed genetically(More)
Individual cell heterogeneity is commonly observed within populations, although its molecular basis is largely unknown. Previously, using FRET-based microscopy, we observed heterogeneity in cellular c-di-GMP levels. In this study, we show that c-di-GMP heterogeneity in Pseudomonas aeruginosa is promoted by a specific phosphodiesterase partitioned after cell(More)
We study discrimination against immigrants using micro-level data from Switzer-land, where, until recently, some municipalities used referenda to decide on the citizenship applications of their foreign residents. We show that naturalization decisions vary dramatically with the attributes of the immigrants, which we collect from official applicant(More)
W e study discrimination against immigrants using microlevel data from Switzerland, where, until recently, some municipalities used referendums to decide on the citizenship applications of foreign residents. We show that naturalization decisions vary dramatically with immigrants' attributes, which we collect from official applicant descriptions that voters(More)
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