Matthias Backenstrass

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Quantitative magnetic resonance imaging (MRI) was used to investigate volumes of different brain structures in 19 patients with late-onset major depression (DSM-III-R), 27 patients with Alzheimer's disease (NINCDS-ADRDA criteria) and 13 age matched controls. 3-D MRI sequences were acquired using a Siemens 1.5 T scanner. Whole brain volume, CSF volume,(More)
BACKGROUND Milder forms of depression are highly prevalent in the clinical setting as well as in primary care. However, it is still unclear whether there are distinguishable groups among the various subthreshold syndromes and to what extent they are associated with impairment, thus requiring treatment. Therefore, the study aimed at comparing the degree of(More)
BACKGROUND The impending revisions of DSM-IV and ICD-10 provide an excellent opportunity to improve the diagnostic accuracy of the current somatoform disorder classification. To prepare for these revisions, this study systematically investigates the validity of the current classification of somatoform disorders. METHODS We searched Medline, Psycinfo and(More)
BACKGROUND Borderline personality disorder is associated with subtle neuropsychological deficits. A potential impairment of response inhibition is of major interest, since it could be related to impulsivity as a clinical feature of borderline personality disorder. SAMPLING AND METHODS Response inhibition was studied in an auditory Go/Nogo paradigm in a(More)
The purpose of this study was to objectify some of the personality dimensions of the typus melancholicus (TM) personality formation in endogenous depressives and to compare the consistency of the term used in questionnaires with the original concept as delineated in our preceding paper. The prevalence of TM in endogenous-depressive inpatients was 51% for(More)
OBJECTIVE The study presents data on the 3-month prevalences of postpartum anxiety disorders (PAD) and postpartum depressive disorders (PDD) and their comorbidity in a German community sample. Associations with sociodemographic variables and previous history of psychopathology were analysed. METHOD Data were gathered in a longitudinal study over the first(More)
Based on cognitive concepts of personality disorders as well as on the bio-social model of borderline personality disorder (BPD), a 34-item instrument, the questionnaire of thoughts and feelings (QTF) was developed for the assessment of feelings, strategic cognitions, and assumptions characteristic for BPD. In different studies, item- and factor analyses(More)
BACKGROUND Osteoarthritis (OA) is highly prevalent and has substantial impact on quality of life as well as on healthcare costs. The general practitioner (GP) often is the first care provider for patients with this chronic disease. The aim of this study was to identify health care needs of patients with OA and to reveal possible obstacles for improvements(More)
BACKGROUND The purpose of this study was to assess whether planning and problem-solving training is more effective in improving functional capacity in patients with schizophrenia than a training program addressing basic cognitive functions. METHODS Eighty-nine patients with schizophrenia were randomly assigned either to a computer assisted training of(More)
BACKGROUND Studies show that subthreshold depression is highly prevalent in primary care, has impact on the quality of life and causes immense health care costs. Although this points to the clinical relevance of subthreshold depression, contradictory results exist regarding the often self-remitting course of this state. However, first steps towards quality(More)