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We describe the application of assumption-based argumenta-tion (ABA) to a domain of medical knowledge derived from clinical trials of drugs for breast cancer. We adapt an algorithm for calculating the admissible semantics for ABA frameworks to take account of preferences and describe a prototype implementation which uses variant-based parallel computation(More)
Cryptococcus neoformans is an opportunistic fungal pathogen that causes serious human disease in immunocompromised populations. Its polysaccharide capsule is a key virulence factor which is regulated in response to growth conditions, becoming enlarged in the context of infection. We used microarray analysis of cells stimulated to form capsule over a range(More)
6 Recent advances in technology have produced a significant increase in the avail-7 ability of free sensor data over the Internet. With affordable weather monitoring 8 stations now available to individual meteorology enthusiasts, a reservoir of real 9 time data such as temperature, rainfall and wind speed can now be obtained for 10 most of the world.(More)
  • Jing Huang, Becky, Liz, Jan Cay, Karla, Robin Gau +22 others
  • 1998
We propose a new image feature called the color correlogram as a generic color-spatial indexing tool to tackle various problems that arise in content-based image retrieval and video browsing. Informally speaking, a correlogram represents the spatial correlation of colors in an image. While the computing and storage costs of correlograms match those of(More)
Two approaches to breast cancer prognosis: • Argumentation: reasoning is clear but hard to weigh up • Statistical: reliable conclusions, unclear chain of inference a combination might offer clarity and reliability Two approaches to combining: • Integrated framework: start from scratch • Modular framework: off the shelf, simpler, customisable Data +(More)
We introduce a novel Ontology-based Argumentation Framework (OAF) that links a logic-based argumentation formalism and description logic ontologies. We show how these two formalisms can be tightly coupled by observing a few simple restrictions, and provides features not available in either formalism alone. Our work is evaluated in a large case study on(More)
Web-based distributed modelling architectures are gaining increasing recognition as potentially useful tools to build holistic environmental models, combining individual components in complex workflows. However, existing web-based modelling frameworks currently offer no support for managing uncertainty. On the other hand, the rich array of modelling(More)
This paper specifies, designs and critically evaluates two tools for the automated identification of demographic data (age, occupation and social class) from the profile descriptions of Twitter users in the United Kingdom (UK). Meta-data data routinely collected through the Collaborative Social Media Observatory (COSMOS: http://www.cosmosproject.net/)(More)
OBJECTIVES Evidence-based decision making is becoming increasingly important in healthcare. Much valuable evidence is in the form of the results from clinical trials that compare the relative merits of treatments. In this paper, we present a new framework for representing and synthesizing knowledge from clinical trials involving multiple outcome indicators.(More)